Gene: AT1G26830 (Arabidopsis thaliana)

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Gene Identifier
AT1G26830
Transcript Identifier
AT1G26830.1
Gene Type
Coding gene
Location
Chr1 : 9296063-9298374 : positive

Family Information

Homologous gene family
HOM04x5M000423
(437 genes in 39 species)
specific family
Orthologous gene family
ORTHO04x5M002711
(102 genes in 39 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
cullin 3
Curated Summary
Cullin, putative, similar to Cullin homolog 3 (CUL-3) SP:Q13618, GI:3639052 from (Homo sapiens); contains Pfam profile PF00888: Cullin family. Interacts with other components of E3 ligase complex suggesting it functions in RUB-modification. Forms complexes with BTB domain proteins forming a novel class of E3-based ubiquitin protein-ligase complexes. Mutant is early flowering and has a reduced sensitivity to far-red light. cul3a/cul3b homozygous/heterozygous plants are embryo lethal.
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Identifiers

Type Value
AliasATCUL3A,cullin 3A,ATCUL3,cullin 3,CUL3A,cullin 3A
DbxrefPMID:11019805,PMID:15118728,PMID:15659098,PMID:15772280,PMID:15749712,PMID:15923347,PMID:16045478,PMID:16091151,PMID:16280546,PMID:17307927,gene:3435278,UniProt:Q9ZVH4
symbolCUL3
tidAT1G26830.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006511
IBA
TAS
Gene Ontologyubiquitin-dependent protein catabolic process1 2 3
GO:0006511
IEA
InterProubiquitin-dependent protein catabolic process
GO:0009639
IMP
Gene Ontologyresponse to red or far red light4 5
GO:0009911
IMP
Gene Ontologypositive regulation of flower development4 5
GO:0009793
IGI
Gene Ontologyembryo development ending in seed dormancy6 7
GO:0009960
IGI
Gene Ontologyendosperm development6 7
GO:0043161
IBA
Gene Ontologyproteasome-mediated ubiquitin-dependent protein catabolic process1
GO:0031146
IBA
Gene OntologySCF-dependent proteasomal ubiquitin-dependent protein catabolic process1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031625
IBA
Gene Ontologyubiquitin protein ligase binding1
GO:0031625
IEA
InterProubiquitin protein ligase binding
GO:0004842
ISS
Gene Ontologyubiquitin-protein transferase activity8
GO:0005515
IPI
Gene Ontologyprotein binding9 10

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISM
Gene Ontologynucleus11
GO:0000151
TAS
Gene Ontologyubiquitin ligase complex2 3
GO:0019005
IPI
Gene OntologySCF ubiquitin ligase complex4 5
GO:0005829
IDA
Gene Ontologycytosol12 13
GO:0031461
IBA
Gene Ontologycullin-RING ubiquitin ligase complex1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR036388Winged helix-like DNA-binding domain superfamily
IPR019559Cullin protein, neddylation domain
IPR001373Cullin, N-terminal
IPR016158Cullin homology domain
IPR036390Winged helix DNA-binding domain superfamily
IPR036317Cullin homology domain superfamily
IPR016159Cullin repeat-like-containing domain superfamily

Mapman id Description
19.2.2.8.2.1Protein homeostasis.ubiquitin-proteasome system.ubiquitin-fold protein conjugation.Cullin-based ubiquitylation complexes.CUL3-BTB E3 ligase complexes.scaffold component CUL3