This entry includes a group of plant microtubule-associated proteins, including TORTIFOLIA1/SPIRAL2 and SPIRAL2-like (SP2L) from Arabidopsis. They regulate the orientation of cortical microtubules and the direction of organ growth [1].

TORTIFOLIA1-like protein 1 (also known as SPIRAL2) is a microtubule-associated protein (MAP) that regulates the orientation of cortical microtubules and the direction of organ growth [2] and may regulate katanin-based microtubule (MT) severing [2]. During virus infection, it may stabilize MT crossovers to support the formation and intercellular spread of the viral RNA complexes [3].

1. Arabidopsis SPIRAL2 promotes uninterrupted microtubule growth by suppressing the pause state of microtubule dynamics. J. Cell. Sci. 121, 2372-81
2. SPIRAL2 determines plant microtubule organization by modulating microtubule severing. Curr. Biol. 23, 1902-7
3. Experimental virus evolution reveals a role of plant microtubule dynamics and TORTIFOLIA1/SPIRAL2 in RNA trafficking. PLoS ONE 9, e105364

This entry includes a group of plant microtubule-associated proteins, including TORTIFOLIA1/SPIRA
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