Among the different families of transporter, only two occur ubiquitously in all classifications of organisms. These are the ATP-Binding Cassette (ABC) superfamily and the Major Facilitator Superfamily (MFS). The MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients [1, 2].

1. Major facilitator superfamily. Microbiol. Mol. Biol. Rev. 62, 1-34
2. Sugar transporters from bacteria, parasites and mammals: structure-activity relationships. Trends Biochem. Sci. 23, 476-81

Among the different families of transporter, only two occur ubiquitously in all classifications o
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