Dicots PLAZA 4.5 gene overview : AT5G44750

Gene: AT5G44750 (Arabidopsis thaliana)

Overview

Gene Identifier: AT5G44750
Transcript Identifier: AT5G44750.1
Gene Type: Coding gene
Location: Chr5 : 18052669-18059581 : positive

Family Information

Homologous gene family: HOM04D004212
(83 genes in 55 species)
specific family

Descriptions

Description: DNA-directed DNA polymerase

Curated Summary: Homologous to Y-family DNA polymerases, contains BRCT domain. Mutants are sensitive to UV-B radiation. Gene is involved in damage-tolerance mechanisms through translesion synthesis(TLS).

Identifiers

Type	Value
symbol	REV1
tid	AT5G44750.1

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Biological Process

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0006281	ISS IEA	Gene Ontology	DNA repair	1 2
GO:0006281	IEA	InterPro	DNA repair
GO:0071897	IEA	Gene Ontology	DNA biosynthetic process	2
GO:0006974	IMP	UniProt	cellular response to DNA damage stimulus
GO:0006974	IMP	Gene Ontology	cellular response to DNA damage stimulus	3
GO:0010224	IMP	UniProt	response to UV-B
GO:0010224	IMP	Gene Ontology	response to UV-B	3
GO:0042276	IEA	UniProt	error-prone translesion synthesis
GO:0042276	IEA	InterPro	error-prone translesion synthesis

Molecular Function

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0003684	IEA	UniProt	damaged DNA binding
GO:0003684	IEA	Gene Ontology	damaged DNA binding	4
GO:0003684	IEA	InterPro	damaged DNA binding
GO:0046872	IEA	UniProt	metal ion binding
GO:0046872	IEA	Gene Ontology	metal ion binding	2
GO:0003887	IDA	UniProt	DNA-directed DNA polymerase activity
GO:0003887	IDA	Gene Ontology	DNA-directed DNA polymerase activity	5
GO:0016779	IEA	InterPro	nucleotidyltransferase activity

Cellular Component

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0005634	IEA	UniProt	nucleus
GO:0005634	ISM IEA	Gene Ontology	nucleus	6 7

Color Legend

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR001357	BRCT domain
IPR017961	DNA polymerase, Y-family, little finger domain
IPR001126	UmuC domain
IPR012112	DNA repair protein Rev1

Mapman id	Description
14.2.5	.DNA damage response.DNA repair polymerase activities.DNA polymerase (REV1)