Gene: AT5G02100 (Arabidopsis thaliana)

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Gene Identifier
AT5G02100
Transcript Identifier
AT5G02100.1
Gene Type
Coding gene
Location
Chr5 : 413639-416016 : positive

Family Information

Homologous gene family
HOM04D002144
(149 genes in 54 species)
specific family
Orthologous gene family
ORTHO04D002615
(136 genes in 54 species)
specific family

Descriptions

Description
Oxysterol-binding family protein
Curated Summary
Encodes a protein that binds to beta-sitosterol and localizes to the ER. The WFDE motif in ORP3a appears to be important for a direct interaction with PVA12 [Plant VAMP-Associated protein 12]. Mutation of this motif causes ORP3a to relocalize to the Golgi and cytosol. The interaction between PVA12 and ORP3a does not appear to be sterol-dependent.
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Identifiers

Type Value
AliasORP3A,OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 3A
full_nameUNFERTILIZED EMBRYO SAC 18
symbolUNE18
tidAT5G02100.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006869
IEA
UniProtlipid transport
GO:0006869
IEA
Gene Ontologylipid transport1
GO:0007338
IEA
UniProtsingle fertilization
GO:0007338
IEA
Gene Ontologysingle fertilization1
GO:0008202
ISS
Gene Ontologysteroid metabolic process2
GO:0009567
IMP
UniProtdouble fertilization forming a zygote and endosperm
GO:0009567
IMP
Gene Ontologydouble fertilization forming a zygote and endosperm3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008142
ISS
Gene Ontologyoxysterol binding2
GO:0005515
IPI
Gene Ontologyprotein binding4
GO:0032934
IDA
UniProtsterol binding
GO:0032934
IDA
Gene Ontologysterol binding4

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISM
Gene Ontologynucleus5
GO:0005794
IEA
UniProtGolgi apparatus
GO:0005794
IEA
Gene OntologyGolgi apparatus6
GO:0005783
IDA
UniProtendoplasmic reticulum
GO:0005783
IDA
Gene Ontologyendoplasmic reticulum4
GO:0005829
RCA
Gene Ontologycytosol7

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000648Oxysterol-binding protein
IPR018494Oxysterol-binding protein, conserved site

Mapman id Description
5.8.1.1.Lipid metabolism.lipid trafficking.endoplasmic reticulum-plasma membrane lipid transfer.lipid transfer protein (ORP3a)