Gene: AT3G04740 (Arabidopsis thaliana)

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Gene Identifier
AT3G04740
Transcript Identifier
AT3G04740.1
Gene Type
Coding gene
Location
Chr3 : 1294037-1300555 : positive

Family Information

Homologous gene family
HOM04D003457
(96 genes in 54 species)
specific family

Descriptions

Description
RNA polymerase II transcription mediator
Curated Summary
encodes a protein with similarities to subunits of the Mediator complex, required for RNA polymerase II recruitment at target promoters in response to specific activators. Lines carrying loss of function mutations in the gene have reduced cell numbers in aerial organs. On the other hand, lines overexpressing the gene have increased number of small cells in clusters, suggesting cell division is more unsynchronized in the overexpressors.Required for expression of CBF-controlled cold-responsive genes. Required for recruitment of the Mediator complex and RNA polymerase II to CBF-controlled cold-responsive genes. Required for expression of some dark-upregulated genes.
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Identifiers

Type Value
AliasATMED14,ARABIDOPSIS MEDIATOR COMPONENTS 14,MED14,MEDIATOR COMPONENTS 14
full_nameSTRUWWELPETER
symbolSWP
tidAT3G04740.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006351
IEA
UniProttranscription, DNA-templated
GO:0006351
IEA
Gene Ontologytranscription, DNA-templated1
GO:0006357
IEA
Gene Ontologyregulation of transcription from RNA polymerase II promoter2
GO:0006357
IEA
InterProregulation of transcription from RNA polymerase II promoter
GO:0007275
IEA
UniProtmulticellular organism development
GO:0007275
IEA
Gene Ontologymulticellular organism development1
GO:0040008
IEA
UniProtregulation of growth
GO:0040008
IEA
Gene Ontologyregulation of growth1
GO:0008284
IMP
UniProtpositive regulation of cell proliferation
GO:0008284
IMP
Gene Ontologypositive regulation of cell proliferation3
GO:0045893
ISS
Gene Ontologypositive regulation of transcription, DNA-templated3
GO:0009627
IEP
UniProtsystemic acquired resistance
GO:0009627
IEP
Gene Ontologysystemic acquired resistance4
GO:0009631
IMP
UniProtcold acclimation
GO:0009631
IMP
Gene Ontologycold acclimation5 6

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001104
IBA
UniProtRNA polymerase II transcription cofactor activity
GO:0001104
IBA
Gene OntologyRNA polymerase II transcription cofactor activity7
GO:0001104
IEA
InterProRNA polymerase II transcription cofactor activity
GO:0005515
IPI
Gene Ontologyprotein binding8

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISM
Gene Ontologynucleus9
GO:0070847
IBA
UniProtcore mediator complex
GO:0070847
IBA
Gene Ontologycore mediator complex7
GO:0016592
IDA
UniProtmediator complex
GO:0016592
IDA
ISS
Gene Ontologymediator complex3 10
GO:0016592
IEA
InterPromediator complex
GO:0009506
IDA
UniProtplasmodesma
GO:0009506
IDA
Gene Ontologyplasmodesma11

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR013947Mediator complex, subunit Med14

Mapman id Description
15.3.3.3.4.RNA biosynthesis.RNA polymerase II-dependent transcription.MEDIATOR transcription co-activator complex.tail module.component MED14