Gene: AT2G44180 (Arabidopsis thaliana)

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Gene Identifier
AT2G44180
Transcript Identifier
AT2G44180.1
Gene Type
Coding gene
Location
Chr2 : 18269442-18271785 : negative

Family Information

Homologous gene family
HOM04D003336
(99 genes in 54 species)
specific family
Orthologous gene family
ORTHO04D004345
(92 genes in 54 species)
specific family
Duplication type
Block duplicate

Descriptions

Description
methionine aminopeptidase 2A
Curated Summary
Encodes a MAP2 like methionine aminopeptidase. In MAP1A mutant background plants show an increased sensitivity to fumagillin resulting in defects in development. Phenotype is similar to RNAi lines which knock out all MAP2/MAP1 loci.
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Identifiers

Type Value
symbolMAP2A
tidAT2G44180.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006508
IEA
Gene Ontologyproteolysis1
GO:0006508
IEA
InterProproteolysis
GO:0031365
TAS
UniProtN-terminal protein amino acid modification
GO:0031365
TAS
Gene OntologyN-terminal protein amino acid modification2
GO:0070084
IEA
UniProtprotein initiator methionine removal

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004177
IEA
UniProtaminopeptidase activity
GO:0004177
IEA
Gene Ontologyaminopeptidase activity1
GO:0004177
IEA
InterProaminopeptidase activity
GO:0008235
IEA
UniProtmetalloexopeptidase activity
GO:0008235
IEA
Gene Ontologymetalloexopeptidase activity3
GO:0008235
IEA
InterPrometalloexopeptidase activity
GO:0046872
IEA
UniProtmetal ion binding
GO:0046872
IEA
Gene Ontologymetal ion binding1
GO:0070006
IEA
UniProtmetalloaminopeptidase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
UniProtcytoplasm
GO:0005737
IDA
ISM
Gene Ontologycytoplasm4 5

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002468Peptidase M24A, methionine aminopeptidase, subfamily 2
IPR000994Peptidase M24
IPR001714Peptidase M24, methionine aminopeptidase
IPR018349Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site
IPR011991Winged helix-turn-helix DNA-binding domain

Mapman id Description
19.4.5.6.2.Protein homeostasis.proteolysis.metallopeptidase activities.aminopeptidase activities.M24-class methionyl aminopeptidase (MAP2)