Gene: AT1G80360 (Arabidopsis thaliana)

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Gene Identifier
AT1G80360
Transcript Identifier
AT1G80360.2
Gene Type
Coding gene
Location
Chr1 : 30208736-30210643 : negative

Family Information

Homologous gene family
HOM04D004634
(78 genes in 53 species)
specific family

Descriptions

Description
Pyridoxal phosphate (PLP)-dependent transferases superfamily protein
Curated Summary
Encodes a methionine-specific aminotransferase that uses the ethylene biosynthetic intermediate methionine as an amino donor and the auxin biosynthetic intermediate indole-3-pyruvic acid as an amino acceptor to produce L-tryptophan and 2-oxo-4-methylthiobutyric acid. These actions allow VAS1 to coordinate both auxin and ethylene biosynthesis. It functions downstream of TAA1/SAV3 but upstream of YUCs to negatively modulate IAA biosynthesis directly by altering the 3-IPA pool.
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Identifiers

Type Value
AliasVAS1,reversal of sav3 phenotype 1
tidAT1G80360.2

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009641
IMP
Gene Ontologyshade avoidance1
GO:0009851
IMP
Gene Ontologyauxin biosynthetic process1
GO:0010366
IMP
Gene Ontologynegative regulation of ethylene biosynthetic process1
GO:1901997
IDA
Gene Ontologynegative regulation of indoleacetic acid biosynthetic process via tryptophan1
GO:0009058
IEA
InterProbiosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008483
ISS
Gene Ontologytransaminase activity2
GO:0030170
IEA
Gene Ontologypyridoxal phosphate binding3
GO:0030170
IEA
InterPropyridoxal phosphate binding
GO:0010326
IDA
Gene Ontologymethionine-oxo-acid transaminase activity1
GO:0003824
IEA
InterProcatalytic activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
ISM
Gene Ontologycytoplasm1 4
GO:0005829
IDA
Gene Ontologycytosol5

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR015421Pyridoxal phosphate-dependent transferase, major region, subdomain 1
IPR015422Pyridoxal phosphate-dependent transferase, subdomain 2
IPR004839Aminotransferase, class I/classII
IPR004838Aminotransferases, class-I, pyridoxal-phosphate-binding site
IPR015424Pyridoxal phosphate-dependent transferase

Mapman id Description
4.2.8.1.Amino acid metabolism.degradation.aromatic amino acid.aromatic-amino-acid aminotransferase