Gene: AT1G13980 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G13980
Transcript Identifier
AT1G13980.1
Gene Type
Coding gene
Location
Chr1 : 4789587-4794397 : positive

Family Information

Homologous gene family
HOM04D000483
(524 genes in 55 species)
specific family
Orthologous gene family
ORTHO04D001428
(200 genes in 55 species)
specific family

Descriptions

Description
sec7 domain-containing protein
Curated Summary
Encodes a GDP/GTP exchange factor for small G-proteins of the ADP ribosylation factor (RAF) class, and as regulator of intracellular trafficking. Homologous to Sec7p and YEC2 from yeast. Involved in the specification of apical-basal pattern formation. Essential for cell division, expansion and adhesion. It appears that heteotypic binding between the DCB and C-terminal domains of two GNOM proteins is required for membrane association, however, GNOM appears to exist predominantly as a heterodimer formed through DCB-DCB interactions.
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Identifiers

Type Value
AliasEMB30,EMBRYO DEFECTIVE 30,VAN7,VASCULAR NETWORK 7
full_nameGNOM
symbolGN
tidAT1G13980.1

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0015031
IEA
UniProtprotein transport
GO:0015031
IEA
Gene Ontologyprotein transport1
GO:0032012
IEA
UniProtregulation of ARF protein signal transduction
GO:0032012
IEA
Gene Ontologyregulation of ARF protein signal transduction2
GO:0032012
IEA
InterProregulation of ARF protein signal transduction
GO:0010087
IMP
UniProtphloem or xylem histogenesis
GO:0010087
IMP
Gene Ontologyphloem or xylem histogenesis3
GO:0007155
IMP
UniProtcell adhesion
GO:0007155
IMP
Gene Ontologycell adhesion4
GO:0071555
IMP
UniProtcell wall organization
GO:0071555
IMP
Gene Ontologycell wall organization4
GO:0016192
IMP
UniProtvesicle-mediated transport
GO:0016192
IMP
Gene Ontologyvesicle-mediated transport5
GO:0032509
IMP
UniProtendosome transport via multivesicular body sorting pathway
GO:0032509
IMP
Gene Ontologyendosome transport via multivesicular body sorting pathway5
GO:0048209
TAS
UniProtregulation of vesicle targeting, to, from or within Golgi
GO:0048209
TAS
Gene Ontologyregulation of vesicle targeting, to, from or within Golgi6
GO:0001736
IGI
UniProtestablishment of planar polarity
GO:0001736
IGI
Gene Ontologyestablishment of planar polarity7
GO:0048765
IGI
UniProtroot hair cell differentiation
GO:0048765
IGI
Gene Ontologyroot hair cell differentiation7
GO:0010311
IMP
UniProtlateral root formation
GO:0010311
IMP
Gene Ontologylateral root formation8
GO:0010540
IMP
UniProtbasipetal auxin transport
GO:0010540
IMP
Gene Ontologybasipetal auxin transport8
GO:0006897
IMP
UniProtendocytosis
GO:0006897
IMP
Gene Ontologyendocytosis9
GO:0000911
IMP
UniProtcytokinesis by cell plate formation
GO:0000911
IMP
Gene Ontologycytokinesis by cell plate formation10
GO:0009793
IMP
UniProtembryo development ending in seed dormancy
GO:0009793
IMP
Gene Ontologyembryo development ending in seed dormancy10
GO:0009826
IMP
UniProtunidimensional cell growth
GO:0009826
IMP
Gene Ontologyunidimensional cell growth10
GO:0009880
IMP
UniProtembryonic pattern specification
GO:0009880
IMP
Gene Ontologyembryonic pattern specification10
GO:0009942
IMP
UniProtlongitudinal axis specification
GO:0009942
IMP
Gene Ontologylongitudinal axis specification10
GO:0010274
IMP
UniProthydrotropism

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005086
IDA
UniProtARF guanyl-nucleotide exchange factor activity
GO:0005086
IDA
Gene OntologyARF guanyl-nucleotide exchange factor activity11
GO:0005086
IEA
InterProARF guanyl-nucleotide exchange factor activity
GO:0010292
IGI
Gene OntologyGTP:GDP antiporter activity11
GO:0005515
IPI
Gene Ontologyprotein binding12
GO:0042802
IPI
UniProtidentical protein binding
GO:0042802
IPI
Gene Ontologyidentical protein binding12
GO:0042803
IPI
UniProtprotein homodimerization activity
GO:0042803
IPI
Gene Ontologyprotein homodimerization activity13
GO:0005488
IEA
InterProbinding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISM
Gene Ontologycytoplasm14
GO:0005802
IBA
UniProttrans-Golgi network
GO:0005802
IBA
Gene Ontologytrans-Golgi network15
GO:0005829
IEA
UniProtcytosol
GO:0005829
IEA
Gene Ontologycytosol16
GO:0010008
IEA
UniProtendosome membrane
GO:0010008
IEA
Gene Ontologyendosome membrane16
GO:0005768
IDA
UniProtendosome
GO:0005768
IDA
Gene Ontologyendosome5
GO:0005886
IDA
UniProtplasma membrane
GO:0005886
IDA
Gene Ontologyplasma membrane9

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011989Armadillo-like helical
IPR023394Sec7 domain, alpha orthogonal bundle
IPR032691Guanine nucleotide exchange factor, N-terminal
IPR000904Sec7 domain
IPR016024Armadillo-type fold

Mapman id Description
22.3.3.1.Vesicle trafficking.Coat protein I (COPI) coatomer machinery.ARF-GTPase guanyl-nucleotide exchange factor (ARF-GEF) activities.ARF-GEF factor (GBF)