The plant hormone auxin (indole-3-acetic acid) can regulate the gene expression of several gene families. Two protein families, Aux/IAA proteins and the auxin response factors (ARF), are key regulators of auxin-modulated gene expression, and are related to one another [1]. ARFs (IPR010525) can activate or repress transcription by directly binding to DNA cis-acting promoter elements, while Aux/IAA proteins (IPR003311) are thought to repress auxin-induced gene expression through their interactions with ARFs. Aux/IAA and ARF are thought to interact with each other through C-terminal protein-protein interaction domains found in both Aux/IAA and ARF; this entry represents the dimerisation domain.

1. Genetics of Aux/IAA and ARF action in plant growth and development. Plant Mol. Biol. 49, 387-400

The plant hormone auxin (indole-3-acetic acid) can regulate the gene expression of several gene f
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