Gene: AT5G50700 (Arabidopsis thaliana)

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Gene Identifier
AT5G50700
Transcript Identifier
AT5G50700.1
Gene Type
Coding gene
Location
5 : 20623259-20624995 : negative

Family

Gene family
HOM03M000595
(113 genes in 15 species)
specific family
Duplication type
Tandem duplicate

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Descriptions

Description
hydroxysteroid dehydrogenase 1
Curated Summary
Encodes a hydroxysteroid dehydrogenase HSD1. Two copies of HSD1 (At5g50600 and At5g50700) exist in the Arabidopsis genome as a result of an exact 33-kb duplication on chromosome 5 encompassing seven genes. There are five homologs of HSD1 in Arabidopsis (HSD2-At3g47350, HSD3-At3g47360, HSD4-At5g50590, HSD4-At5g50690 and HSD6-At5g50770; HSD4 has two copies due to the same gene duplication event occurred to HSD1) (Plant Cell Physiology 50:1463). At5g50690 is also named as HSD7 (Plant Physiology 145:87). HSD1 is identified from the proteome of oil bodies from mature seeds. Transcription of HSD1 is specifically and highly induced in oil-accumulating tissues of mature seeds; transcript disappears during germination.
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Identifiers

Identifier Name
aliasHSD1
aliashydroxysteroid dehydrogenase 1
uniprotP0DKC6
uniprotP0DKC5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006694IEAUniProtsteroid biosynthetic process1 2 3 4 5
GO:0008152IEAInterPrometabolic process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016491ISS, IEAGene Ontologyoxidoreductase activity1
GO:0070524IEAUniProt11-beta-hydroxysteroid dehydrogenase (NADP+) activity1 2 3 4 5

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0016021IEAUniProtintegral to membrane1 2 3 4 5
GO:0005811IEAUniProtlipid particle1 2 3 4 5

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002198Short-chain dehydrogenase/reductase SDR
IPR002347Glucose/ribitol dehydrogenase
IPR016040NAD(P)-binding domain
IPR020904Short-chain dehydrogenase/reductase, conserved site

Mapman id Description
26.22misc.short chain dehydrogenase/reductase (SDR)
No SignalP domains detected for this gene.