Gene: AT5G50320 (Arabidopsis thaliana)

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Gene Identifier
AT5G50320
Transcript Identifier
AT5G50320.1
Gene Type
Coding gene
Location
5 : 20481200-20484811 : negative

Family

Gene family
HOM03M005429
(19 genes in 15 species)
specific family

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Descriptions

Description
radical SAM domain-containing protein / GCN5-related N-acetyltransferase (GNAT) family protein
Curated Summary
A subunit of Elongator, a histone acetyl transferase complex, consisting of six subunits (ELP1?ELP6), that copurifies with the elongating RNAPII in yeast and humans. Three Arabidopsis thaliana genes, encoding homologs of the yeast Elongator subunits ELP1, ELP3 (histone acetyl transferase), and ELP4 are responsible for the narrow leaf phenotype in elongata mutants and for reduced root growth that results from a decreased cell division rate. Two lines with RNAi constructs directed against HAG3 grow normally and can produce root calli, but have defects in agrobacterium-mediated transformation.
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Identifiers

Identifier Name
aliasHISTONE ACETYLTRANSFERASE OF THE GNAT FAMILY 3
aliasELO3
aliasHISTONE ACETYLTRANSFERASE 8
aliasHAG3
aliasELONGATA 3
aliasELP3
aliasEAST1
aliasElongator protein 3
aliasenhancer-of-asymmetric leaves-two 1
aliasAtELP3
aliasHAC8
uniprotQ93ZR1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0008283IMPUniProtcell proliferation1 2 3 4 5 6 7 8
GO:0035265IMPUniProtorgan growth1 2 3 4 5 6 7 8
GO:0009294IMPUniProtDNA mediated transformation1 2 3 4 5 6 7 8
GO:0010928IMPUniProtregulation of auxin mediated signaling pathway1 2 3 4 5 6 7 8
GO:0002098IMPUniProttRNA wobble uridine modification1 2 3 4 5 6 7 8
GO:0010084IMPUniProtspecification of organ axis polarity1 2 3 4 5 6 7 8
GO:2000025IMPUniProtregulation of leaf formation1 2 3 4 5 6 7 8
GO:0051604RCAGene Ontologyprotein maturation1
GO:0009734IEAUniProtauxin mediated signaling pathway1 2 3 4 5 6 7
GO:0016573IEAUniProthistone acetylation1 2 3 4 5 6 7
GO:0006355IEAUniProtregulation of transcription, DNA-dependent1 2 3 4 5 6 7
GO:0006351IEAUniProttranscription, DNA-templated1 2 3 4 5 6 7

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004402IEA, ISSUniProthistone acetyltransferase activity1 2 3 4 5 6 7 8
GO:0051536IEAUniProtiron-sulfur cluster binding1 2 3 4 5 6 7
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5 6 7
GO:0008080IEAInterProN-acetyltransferase activity
GO:0003824IEAInterProcatalytic activity
GO:0051540IEAPLAZA Homologymetal cluster bindingHOM03M005429

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISMGene Ontologynucleus1 2
GO:0005719IDAUniProtnuclear euchromatin1 2 3 4 5 6 7 8
GO:0033588IDAUniProtElongator holoenzyme complex1 2 3 4 5 6 7 8
GO:0005829IDAUniProtcytosol1 2 3 4 5 6 7 8

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR016181Acyl-CoA N-acyltransferase
IPR000182GNAT domain
IPR023404Radical SAM, alpha/beta horseshoe
IPR007197Radical SAM
IPR006638Elongator protein 3/MiaB/NifB
IPR005910Histone acetyltransferase ELP3

Mapman id Description
27.3.54RNA.regulation of transcription.Histone acetyltransferases
No SignalP domains detected for this gene.
DatabaseType
PlnTFDBGNAT