Gene: AT5G46210 (Arabidopsis thaliana)

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Gene Identifier
AT5G46210
Transcript Identifier
AT5G46210.1
Gene Type
Coding gene
Location
5 : 18731569-18736653 : negative

Family

Gene family
HOM03M000391
(156 genes in 16 species)
specific family

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Descriptions

Description
cullin4
Curated Summary
Arabidopsis CULLIN4 (CUL4) forms an E3 ubiquitin ligase with the CDD complex and a common catalytic subunit RBX1 in mediating light control of development. This CUL4-based E3 ligase is essential for the repression of photomorphogenesis. The partial loss of CUL4 function resulted in a constitutive photomorphogenic phenotype with respect to morphogenesis and light-regulated gene expression. CUL4 exhibits a synergistic genetic interaction with COP10 and DET1.
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Identifiers

Identifier Name
aliascullin4
aliasCUL4
aliasATCUL4
uniprotQ8LGH4

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009640IMP, RCA, UniProtphotomorphogenesis1 2 3 4 5 6 7 8 9 10
GO:0048366IMP, RCAGene Ontologyleaf development1 2
GO:0000209IDAUniProtprotein polyubiquitination1 2 3 4 5 6 7 8 9
GO:0009908IMPUniProtflower development1 2 3 4 5 6 7 8 9
GO:0010100IMP, RCA, UniProtnegative regulation of photomorphogenesis1 2 3 4 5 6 7 8 9 10
GO:0048367IMPGene Ontologyshoot system development1
GO:0009755IMP, RCA, UniProthormone-mediated signaling pathway1 2 3 4 5 6 7 8 9 10
GO:0010154IMPGene Ontologyfruit development1
GO:0010182IMP, RCA, UniProtsugar mediated signaling pathway1 2 3 4 5 6 7 8 9 10
GO:0048825IMP, RCA, UniProtcotyledon development1 2 3 4 5 6 7 8 9 10
GO:0006281IMP, RCA, UniProtDNA repair1 2 3 4 5 6 7 8 9 10
GO:0048575IMPUniProtshort-day photoperiodism, flowering1 2 3 4 5 6 7 8 9
GO:0000278RCAGene Ontologymitotic cell cycle1
GO:0006396RCAGene OntologyRNA processing1
GO:0007062RCAGene Ontologysister chromatid cohesion1
GO:0009793RCAGene Ontologyembryo development ending in seed dormancy1
GO:0009845RCAGene Ontologyseed germination1
GO:0009880RCAGene Ontologyembryonic pattern specification1
GO:0009909RCAGene Ontologyregulation of flower development1
GO:0009933RCAGene Ontologymeristem structural organization1
GO:0010072RCAGene Ontologyprimary shoot apical meristem specification1
GO:0010162RCAGene Ontologyseed dormancy process1
GO:0010228RCAGene Ontologyvegetative to reproductive phase transition of meristem1
GO:0010431RCAGene Ontologyseed maturation1
GO:0010564RCAGene Ontologyregulation of cell cycle process1
GO:0016567RCAGene Ontologyprotein ubiquitination1
GO:0019915RCAGene Ontologylipid storage1
GO:0045595RCAGene Ontologyregulation of cell differentiation1
GO:0048608RCAGene Ontologyreproductive structure development1
GO:0050826RCAGene Ontologyresponse to freezing1
GO:0051301RCAGene Ontologycell division1
GO:0009738IEAUniProtabscisic acid-activated signaling pathway1 2 3 4 5 6 7 8
GO:0006511IEAUniProtubiquitin-dependent protein catabolic process1 2 3 4 5 6 7 8
GO:0044265IEAPLAZA Homologycellular macromolecule catabolic processHOM03M000391
GO:0030163IEAPLAZA Homologyprotein catabolic processHOM03M000391
GO:0051603IEAPLAZA Homologyproteolysis involved in cellular protein catabolic processHOM03M000391
GO:0019941IEAPLAZA Homologymodification-dependent protein catabolic processHOM03M000391
GO:0044257IEAPLAZA Homologycellular protein catabolic processHOM03M000391
GO:0043632IEAPLAZA Homologymodification-dependent macromolecule catabolic processHOM03M000391

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005515IPIGene Ontologyprotein binding1
GO:0031625IEAInterProubiquitin protein ligase binding
GO:0044389IEAPLAZA Homologysmall conjugating protein ligase bindingHOM03M000391
GO:0019899IEAPLAZA Homologyenzyme bindingHOM03M000391

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISM, UniProtnucleus1 2 3 4 5 6 7 8 9 10
GO:0080008IPIUniProtCul4-RING ubiquitin ligase complex1 2 3 4 5 6 7 8 9
GO:0000151IPIGene Ontologyubiquitin ligase complex1
GO:0005829IDAUniProtcytosol1 2 3 4 5 6 7 8 9
GO:0031461IEAInterProcullin-RING ubiquitin ligase complex

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001373Cullin, N-terminal
IPR019559Cullin protein, neddylation domain
IPR011991Winged helix-turn-helix DNA-binding domain
IPR016158Cullin homology
IPR016157Cullin, conserved site
IPR016159Cullin repeat-like-containing domain

Mapman id Description
29.5.11.4.3.3protein.degradation.ubiquitin.E3.SCF.cullin
No SignalP domains detected for this gene.