Gene: AT5G37500 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
5 : 14889758-14894883 : negative


Gene family
(197 genes in 16 species)
specific family
Duplication type
Block duplicate

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gated outwardly-rectifying K+ channel
Curated Summary
Encodes a guard cell outward potassium channel. Belongs to the Shaker family K+ channel. This family includes five groups based on phylogenetic analysis (FEBS Letters (2007) 581: 2357): I (inward rectifying channel): AKT1 (AT2G26650), AKT5 (AT4G32500) and SPIK (also known as AKT6, AT2G25600); II (inward rectifying channel): KAT1 (AT5G46240) and KAT2 (AT4G18290); III (weakly inward rectifying channel): AKT2 (AT4G22200); IV (regulatory subunit involved in inwardly rectifying conductance formation): KAT3 (also known as AtKC1, AT4G32650); V (outward rectifying channel): SKOR (AT3G02850) and GORK (AT5G37500). Mutants have increased water consumption and limited stomatal closure in response to abscisic and jasmonic acids. It forms a heteromeric K(out) channels with SKOR. The gene is expressed ubiquitously in root and the vasculature and guard cells of leaves. Expression is suppressed during agrobacterium-induced tumor formation and increased in response to water deprivation and cold.
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Identifier Name
aliasgated outwardly-rectifying K+ channel





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009409IEPUniProtresponse to cold1 2 3 4 5 6 7
GO:0009414IEPUniProtresponse to water deprivation1 2 3 4 5 6 7
GO:0009737IEPUniProtresponse to abscisic acid1 2 3 4 5 6 7
GO:0009753IMPUniProtresponse to jasmonic acid1 2 3 4 5 6 7
GO:0006813IEAInterPropotassium ion transport
GO:0055085IEAInterProtransmembrane transport
GO:0006811IEAInterProion transport

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0030551ISSGene Ontologycyclic nucleotide binding1
GO:0015271IMP, IDAUniProtoutward rectifier potassium channel activity1 2 3 4 5 6 7 8
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0005249IEAInterProvoltage-gated potassium channel activity
GO:0005216IEAInterProion channel activity
GO:0015079IEAPLAZA Homologypotassium ion transmembrane transporter activityHOM03M000275
GO:0022843IEAPLAZA Homologyvoltage-gated cation channel activityHOM03M000275
GO:0022803IEAPLAZA Homologypassive transmembrane transporter activityHOM03M000275
GO:0022839IEAPLAZA Homologyion gated channel activityHOM03M000275
GO:0005244IEAPLAZA Homologyvoltage-gated ion channel activityHOM03M000275
GO:0005261IEAPLAZA Homologycation channel activityHOM03M000275
GO:0022836IEAPLAZA Homologygated channel activityHOM03M000275
GO:0022838IEAPLAZA Homologysubstrate-specific channel activityHOM03M000275
GO:0022832IEAPLAZA Homologyvoltage-gated channel activityHOM03M000275
GO:0005267IEAPLAZA Homologypotassium channel activityHOM03M000275
GO:0015267IEAPLAZA Homologychannel activityHOM03M000275

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISM, UniProtnucleus1 2 3 4 5 6 7 8
GO:0016021IEAUniProtintegral to membrane1 2 3 4 5 6

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR020683Ankyrin repeat-containing domain
IPR003938Potassium channel, voltage-dependent, EAG/ELK/ERG
IPR018490Cyclic nucleotide-binding-like
IPR000595Cyclic nucleotide-binding domain
IPR021789Potassium channel, plant-type
IPR002110Ankyrin repeat
IPR005821Ion transport domain
IPR014710RmlC-like jelly roll fold

Mapman id Description
No SignalP domains detected for this gene.