Gene: AT5G20320 (Arabidopsis thaliana)

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Gene Identifier
AT5G20320
Transcript Identifier
AT5G20320.1
Gene Type
Coding gene
Location
5 : 6859571-6869068 : negative

Family

Gene family
HOM03M000334
(174 genes in 15 species)
specific family

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Descriptions

Description
dicer-like 4
Curated Summary
Encodes an RNase III-like enzyme that catalyzes processing of trans-acting small interfering RNA precursors in a distinct small RNA biogenesis pathway. The protein is also involved in the production of 21-nt primary siRNAs from both inverted-repeat constructs and endogenous sequences, as well as the RDR6-dependent 21-nt secondary siRNAs involved in long-range cell-to-cell signaling. It binds DRB4, a ds-RNA binding protein.
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Identifiers

Identifier Name
aliasDCL4
aliasDICER-LIKE 4
aliasdicer-like 4
aliasATDCL4
uniprotP84634

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006396ISS, RCA, IEAGene OntologyRNA processing1 2
GO:0010050IMP, RCA, UniProtvegetative phase change1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0010267IMP, RCA, UniProtproduction of ta-siRNAs involved in RNA interference1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0010216IMPUniProtmaintenance of DNA methylation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0030422IMP, RCAGene Ontologyproduction of siRNA involved in RNA interference1 2
GO:0051607IMP, RCAGene Ontologydefense response to virus1 2
GO:0035196IGI, RCAGene Ontologyproduction of miRNAs involved in gene silencing by miRNA1 2
GO:0009616IGI, RCA, UniProtvirus induced gene silencing1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0010599IMPUniProtproduction of lsiRNA involved in RNA interference1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0006353IMPUniProtDNA-dependent transcription, termination1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0000278RCAGene Ontologymitotic cell cycle1
GO:0000398RCAGene OntologymRNA splicing, via spliceosome1
GO:0006306RCAGene OntologyDNA methylation1
GO:0006342RCAGene Ontologychromatin silencing1
GO:0006355RCAGene Ontologyregulation of transcription, DNA-dependent1
GO:0007267RCAGene Ontologycell-cell signaling1
GO:0009640RCAGene Ontologyphotomorphogenesis1
GO:0009793RCAGene Ontologyembryo development ending in seed dormancy1
GO:0009845RCAGene Ontologyseed germination1
GO:0009909RCAGene Ontologyregulation of flower development1
GO:0009933RCAGene Ontologymeristem structural organization1
GO:0010162RCAGene Ontologyseed dormancy process1
GO:0010182RCAGene Ontologysugar mediated signaling pathway1
GO:0010228RCAGene Ontologyvegetative to reproductive phase transition of meristem1
GO:0016567RCAGene Ontologyprotein ubiquitination1
GO:0016569RCAGene Ontologycovalent chromatin modification1
GO:0019915RCAGene Ontologylipid storage1
GO:0031047RCAGene Ontologygene silencing by RNA1
GO:0043687RCAGene Ontologypost-translational protein modification1
GO:0045893RCAGene Ontologypositive regulation of transcription, DNA-dependent1
GO:0050826RCAGene Ontologyresponse to freezing1
GO:0090305IEAUniProtnucleic acid phosphodiester bond hydrolysis1 2 3 4 5 6 7 8 9 10 11 12 13 14

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003723IEA, ISSUniProtRNA binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0004525IEA, ISSUniProtribonuclease III activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0008026IEAUniProtATP-dependent helicase activity1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0016891IEAInterProendoribonuclease activity, producing 5'-phosphomonoesters
GO:0004386IEAInterProhelicase activity
GO:0003676IEAInterPronucleic acid binding
GO:0016893IEAPLAZA Homologyendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersHOM03M000334
GO:0004521IEAPLAZA Homologyendoribonuclease activityHOM03M000334

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISM, UniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000999Ribonuclease III domain
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR014720Double-stranded RNA-binding domain
IPR011545DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR001650Helicase, C-terminal
IPR003100Argonaute/Dicer protein, PAZ domain
IPR005034Dicer dimerisation domain
IPR014001Helicase, superfamily 1/2, ATP-binding domain

Mapman id Description
27.1.20RNA.processing.degradation dicer
No SignalP domains detected for this gene.