Gene: AT5G19220 (Arabidopsis thaliana)

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Gene Identifier
AT5G19220
Transcript Identifier
AT5G19220.1
Gene Type
Coding gene
Location
5 : 6463931-6466775 : negative

Family

Gene family
HOM03M000674
(103 genes in 16 species)
specific family

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Descriptions

Description
ADP glucose pyrophosphorylase large subunit 1
Curated Summary
Encodes the large subunit of ADP-glucose pyrophosphorylase which catalyzes the first, rate limiting step in starch biosynthesis. The large subunit plays a regulatory role whereas the small subunit (ApS) is the catalytic isoform. Four isoforms (ApL1-4) have been identified. ApL1 is the major large subunit isoform present in leaves. Mutational analysis of APS1 suggests that APL1 and APL2 can compensate for loss of APS1 catalytic activity,suggesting both have catalytic as well as regulatory functions.
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Identifiers

Identifier Name
aliasADP GLUCOSE PYROPHOSPHORYLASE 2
aliasAPL1
aliasADP glucose pyrophosphorylase large subunit 1
aliasADG2
uniprotP55229

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006098RCAGene Ontologypentose-phosphate shunt1
GO:0006364RCAGene OntologyrRNA processing1
GO:0009637RCAGene Ontologyresponse to blue light1
GO:0009902RCAGene Ontologychloroplast relocation1
GO:0010027RCAGene Ontologythylakoid membrane organization1
GO:0010114RCAGene Ontologyresponse to red light1
GO:0010218RCAGene Ontologyresponse to far red light1
GO:0015979RCAGene Ontologyphotosynthesis1
GO:0019684RCAGene Ontologyphotosynthesis, light reaction1
GO:0034660RCAGene OntologyncRNA metabolic process1
GO:0005978IEAUniProtglycogen biosynthetic process1 2 3 4 5 6
GO:0019252IEAUniProtstarch biosynthetic process1 2 3 4 5 6
GO:0009058IEAInterProbiosynthetic process
GO:0005977IEAPLAZA Homologyglycogen metabolic processHOM03M000674
GO:0006112IEAPLAZA Homologyenergy reserve metabolic processHOM03M000674

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008878IDA, ISSIEA, UniProtglucose-1-phosphate adenylyltransferase activity1 2 3 4 5 6 7 8
GO:0005524IEAUniProtATP binding1 2 3 4 5 6
GO:0016779IEAInterPronucleotidyltransferase activity

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507IDA, ISMGene Ontologychloroplast1 2
GO:0009941IDAUniProtchloroplast envelope1 2 3 4 5 6 7
GO:0009570IDAUniProtchloroplast stroma1 2 3 4 5 6 7

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005836ADP-glucose pyrophosphorylase, conserved site
IPR005835Nucleotidyl transferase
IPR011004Trimeric LpxA-like
IPR011831Glucose-1-phosphate adenylyltransferase

Mapman id Description
2.1.2.1major CHO metabolism.synthesis.starch.AGPase
No SignalP domains detected for this gene.