Gene: AT5G18650 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G18650
Transcript Identifier
AT5G18650.1
Gene Type
Coding gene
Location
5 : 6218260-6220374 : positive

Family

Gene family
HOM03M000544
(121 genes in 16 species)
specific family
Subfamily
ORTHO03M004840
(7 genes in 7 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
CHY-type/CTCHY-type/RING-type Zinc finger protein
Curated Summary
Encodes a RING-type E3 ubiquitin ligase that interacts with and ubiquitinates MYB30, leads to MYB30 proteasomal degradation and downregulation of its transcriptional activity. Since MYB30 is a positive regulator of Arabidopsis HR and defence responses, MIEL1 is involved in the negative regulation of these processes.
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Identifiers

Identifier Name
aliasMIEL1
aliasMYB30-Interacting E3 Ligase 1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0016567IDAGene Ontologyprotein ubiquitination1
GO:1900425IMPGene Ontologynegative regulation of defense response to bacterium1
GO:1901485IDAGene Ontologypositive regulation of transcription factor catabolic process1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008270ISS, IEAGene Ontologyzinc ion binding1
GO:0004842IDAGene Ontologyubiquitin-protein ligase activity1
GO:0008134IPIGene Ontologytranscription factor binding1
GO:0005515IEAInterProprotein binding

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISMGene Ontologynucleus1 2
GO:0005737IDAGene Ontologycytoplasm1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001841Zinc finger, RING-type
IPR008913Zinc finger, CHY-type
IPR017921Zinc finger, CTCHY-type
IPR004039Rubredoxin-type fold
IPR013083Zinc finger, RING/FYVE/PHD-type

Mapman id Description
29.5.11.4.2protein.degradation.ubiquitin.E3.RING
No SignalP domains detected for this gene.