Gene: AT4G34710 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
4 : 16560315-16562450 : negative


Gene family
(28 genes in 14 species)
specific family
Duplication type
Block duplicate

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arginine decarboxylase 2
Curated Summary
encodes a arginine decarboxylase (ADC), a rate-limiting enzyme that catalyzes the first step of polyamine (PA) biosynthesis via ADC pathway in Arabidopsis thaliana. Arabidopsis genome has two ADC paralogs, ADC1 and ADC2. ADC2 is stress-inducible (osmotic stress). Double mutant analysis showed that ADC genes are essential for the production of PA, and are required for normal seed development. Overexpression causes phenotypes similar to GA-deficient plants and these plants show reduced levels of GA due to lower expression levels of AtGA20ox1, AtGA3ox3 and AtGA3ox1.
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Identifier Name
aliasarginine decarboxylase 2





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006596IMPGene Ontologypolyamine biosynthetic process1
GO:0006970IMPGene Ontologyresponse to osmotic stress1
GO:0009611IEP, RCA, UniProtresponse to wounding1 2 3 4
GO:0009737IEPUniProtresponse to abscisic acid1 2 3
GO:0009753IEP, RCA, UniProtresponse to jasmonic acid1 2 3 4
GO:0009651IMPUniProtresponse to salt stress1 2 3
GO:0006979IEP, RCA, UniProtresponse to oxidative stress1 2 3 4
GO:0009446IMPUniProtputrescine biosynthetic process1 2 3
GO:0048316IGIUniProtseed development1 2 3
GO:0009409IMPUniProtresponse to cold1 2 3
GO:0080167IEPUniProtresponse to karrikin1 2 3
GO:0006612RCAGene Ontologyprotein targeting to membrane1
GO:0007165RCAGene Ontologysignal transduction1
GO:0009414RCAGene Ontologyresponse to water deprivation1
GO:0009620RCAGene Ontologyresponse to fungus1
GO:0009695RCAGene Ontologyjasmonic acid biosynthetic process1
GO:0009723RCAGene Ontologyresponse to ethylene1
GO:0009733RCAGene Ontologyresponse to auxin1
GO:0009738RCAGene Ontologyabscisic acid-activated signaling pathway1
GO:0009863RCAGene Ontologysalicylic acid mediated signaling pathway1
GO:0009867RCAGene Ontologyjasmonic acid mediated signaling pathway1
GO:0010363RCAGene Ontologyregulation of plant-type hypersensitive response1
GO:0042538RCAGene Ontologyhyperosmotic salinity response1
GO:0006527IEAUniProtarginine catabolic process1 2
GO:0008295IEAUniProtspermidine biosynthetic process1 2

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008792IMP, IEA, UniProtarginine decarboxylase activity1 2 3
GO:0003824IEAInterProcatalytic activity

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002985Arginine decarboxylase
IPR000183Ornithine/DAP/Arg decarboxylase
IPR022644Orn/DAP/Arg decarboxylase 2, N-terminal
IPR022653Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site
IPR022657Orn/DAP/Arg decarboxylase 2, conserved site
IPR022643Orn/DAP/Arg decarboxylase 2, C-terminal

Mapman id Description
22.1.3polyamine metabolism.synthesis.arginine decarboxylase
No SignalP domains detected for this gene.