Gene: AT4G34580 (Arabidopsis thaliana)

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Gene Identifier
AT4G34580
Transcript Identifier
AT4G34580.1
Gene Type
Coding gene
Location
4 : 16515422-16518527 : positive

Family

Gene family
HOM03M000327
(176 genes in 16 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
Sec14p-like phosphatidylinositol transfer family protein
Curated Summary
Encodes COW1 (can of worms1), a phosphatidylinositol transfer protein essential for root hair tip growth. The N-terminus of the COW1 protein is 32% identical to an essential phosphatidylinositol transfer protein (PITP), the yeast Sec14 protein (sec14p) while the C-terminus is 34.5% identical to a late nodulin of Lotus japonicus, Nlj16. Expression of COW1 complements the growth defect associated with Sec14p dysfunction in yeast. GFP fused to the COW1 protein specifically accumulates at the site of root hair outgrowth.
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Identifiers

Identifier Name
aliasCOW1
aliasSHORT ROOT HAIR 1
aliasSRH1
aliasCAN OF WORMS1
aliasAtSFH1
uniprotF4JLE5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006810ISS, IEAGene Ontologytransport1
GO:0048768IMPUniProtroot hair cell tip growth1 2 3 4 5 6 7 8
GO:0010054RCAGene Ontologytrichoblast differentiation1
GO:0048527RCAGene Ontologylateral root development1
GO:0048589RCAGene Ontologydevelopmental growth1
GO:0048765RCAGene Ontologyroot hair cell differentiation1
GO:0048767RCAGene Ontologyroot hair elongation1
GO:0009932IMPGene Ontologycell tip growth1
GO:0010053IMPGene Ontologyroot epidermal cell differentiation1
GO:0015031IEAUniProtprotein transport1 2 3 4 5 6 7

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005215ISS, IEAGene Ontologytransporter activity1
GO:0008526IGIUniProtphosphatidylinositol transporter activity1 2 3 4 5 6 7 8

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005739ISMGene Ontologymitochondrion1
GO:0000139IEAUniProtGolgi membrane1 2 3 4 5 6 7
GO:0005886IDAUniProtplasma membrane1 2 3 4 5 6 7
GO:0035619IDAUniProtroot hair tip1 2 3 4 5 6 7
GO:0005622IEAInterProintracellular

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001071Cellular retinaldehyde binding/alpha-tocopherol transport
IPR011074CRAL/TRIO, N-terminal domain
IPR001251CRAL-TRIO domain

Mapman id Description
34.99transport.misc
No SignalP domains detected for this gene.