Gene: AT4G22200 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
4 : 11746666-11750091 : negative


Gene family
(197 genes in 16 species)
specific family

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potassium transport 2/3
Curated Summary
Encodes AKT2, a photosynthate- and light-dependent inward rectifying potassium channel with unique gating properties that are regulated by phosphorylation. Expressed in guard cell protoplasts and in the phloem and xylem of aerial portions of the plant. The channel can coassemble with another K+ channel, KAT1, in vitro. In guard cells, AKT2/3 is responsible for the Ca2+ sensitivity of the K+ uptake channel. In the phloem, it regulates the sucrose/H+ symporters via the phloem potential. AKT2 belongs to the Shaker family K+ channels which include the following groups based on phylogenetic analysis (FEBS Letters (2007) 581: 2357): I (inward rectifying channel): AKT1 (AT2G26650), AKT5 (AT4G32500) and SPIK (also known as AKT6, AT2G25600); II (inward rectifying channel): KAT1 (AT5G46240) and KAT2 (AT4G18290); III (weakly inward rectifying channel): AKT2 (AT4G22200); IV (regulatory subunit involved in inwardly rectifying conductance formation): KAT3 (also known as AtKC1, AT4G32650); V (outward rectifying channel): SKOR (AT3G02850) and GORK (AT5G37500).
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Identifier Name
aliaspotassium transport 2/3





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009737IEPUniProtresponse to abscisic acid1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0042391IMPUniProtregulation of membrane potential1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0010264RCAGene Ontologymyo-inositol hexakisphosphate biosynthetic process1
GO:0055085IEAInterProtransmembrane transport
GO:0006813IEAInterPropotassium ion transport
GO:0006811IEAInterProion transport

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005242IDA, ISSGene Ontologyinward rectifier potassium channel activity1 2
GO:0030551ISSGene Ontologycyclic nucleotide binding1
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0042802IPIGene Ontologyidentical protein binding1
GO:0005249IEAUniProtvoltage-gated potassium channel activity1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0005216IEAInterProion channel activity
GO:0015079IEAPLAZA Homologypotassium ion transmembrane transporter activityHOM03M000275
GO:0022843IEAPLAZA Homologyvoltage-gated cation channel activityHOM03M000275
GO:0022803IEAPLAZA Homologypassive transmembrane transporter activityHOM03M000275
GO:0022839IEAPLAZA Homologyion gated channel activityHOM03M000275
GO:0005244IEAPLAZA Homologyvoltage-gated ion channel activityHOM03M000275
GO:0005261IEAPLAZA Homologycation channel activityHOM03M000275
GO:0022836IEAPLAZA Homologygated channel activityHOM03M000275
GO:0022838IEAPLAZA Homologysubstrate-specific channel activityHOM03M000275
GO:0022832IEAPLAZA Homologyvoltage-gated channel activityHOM03M000275
GO:0005267IEAPLAZA Homologypotassium channel activityHOM03M000275
GO:0015267IEAPLAZA Homologychannel activityHOM03M000275

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009506IDAUniProtplasmodesma1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0005789IEAUniProtendoplasmic reticulum membrane1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0016021IEAUniProtintegral to membrane1 2 3 4 5 6 7 8 9 10 11 12 13

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003938Potassium channel, voltage-dependent, EAG/ELK/ERG
IPR002110Ankyrin repeat
IPR000595Cyclic nucleotide-binding domain
IPR020683Ankyrin repeat-containing domain
IPR014710RmlC-like jelly roll fold
IPR005821Ion transport domain
IPR021789Potassium channel, plant-type
IPR018490Cyclic nucleotide-binding-like

Mapman id Description
No SignalP domains detected for this gene.