Gene: AT4G22200 (Arabidopsis thaliana)
Overview 
- Gene Identifier
- AT4G22200
- Transcript Identifier
- AT4G22200.1
- Gene Type
- Coding gene
- Location
- 4 : 11746666-11750091 : negative
Family
- Gene family
Descriptions
- Description
-
potassium transport 2/3
- Curated Summary
-
Encodes AKT2, a photosynthate- and light-dependent inward rectifying potassium channel with unique gating properties that are regulated by phosphorylation. Expressed in guard cell protoplasts and in the phloem and xylem of aerial portions of the plant. The channel can coassemble with another K+ channel, KAT1, in vitro. In guard cells, AKT2/3 is responsible for the Ca2+ sensitivity of the K+ uptake channel. In the phloem, it regulates the sucrose/H+ symporters via the phloem potential. AKT2 belongs to the Shaker family K+ channels which include the following groups based on phylogenetic analysis (FEBS Letters (2007) 581: 2357): I (inward rectifying channel): AKT1 (AT2G26650), AKT5 (AT4G32500) and SPIK (also known as AKT6, AT2G25600); II (inward rectifying channel): KAT1 (AT5G46240) and KAT2 (AT4G18290); III (weakly inward rectifying channel): AKT2 (AT4G22200); IV (regulatory subunit involved in inwardly rectifying conductance formation): KAT3 (also known as AtKC1, AT4G32650); V (outward rectifying channel): SKOR (AT3G02850) and GORK (AT5G37500).
Identifiers
Identifier | Name |
---|---|
alias | AKT2 |
alias | potassium transport 2/3 |
alias | AKT2/3 |
alias | KT2/3 |
alias | AKT3 |
uniprot | Q38898 |
Toolbox
Explore
- ...the colinearity of this gene with other genomes.
- ...the local gene organization for homologous genes.
- ...the phylogenetic tree of the homologous gene family.
- ...the orthologs using the Integrative Orthology Viewer.
- ...the conserved binding sites (upstream/downstream,intron)
View
Biological Process
GO term | Evidence(s) | Provider | Description | Source |
---|---|---|---|---|
GO:0009737 | IEP | UniProt | response to abscisic acid | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 |
GO:0042391 | IMP | UniProt | regulation of membrane potential | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 |
GO:0010264 | RCA | Gene Ontology | myo-inositol hexakisphosphate biosynthetic process | 1 |
GO:0055085 | IEA | InterPro | transmembrane transport | |
GO:0006813 | IEA | InterPro | potassium ion transport | |
GO:0006811 | IEA | InterPro | ion transport |
Molecular Function
GO term | Evidence(s) | Provider | Description | Source |
---|---|---|---|---|
GO:0005242 | IDA, ISS | Gene Ontology | inward rectifier potassium channel activity | 1 2 |
GO:0030551 | ISS | Gene Ontology | cyclic nucleotide binding | 1 |
GO:0005515 | IPI, IEA | Gene Ontology | protein binding | 1 |
GO:0042802 | IPI | Gene Ontology | identical protein binding | 1 |
GO:0005249 | IEA | UniProt | voltage-gated potassium channel activity | 1 2 3 4 5 6 7 8 9 10 11 12 13 |
GO:0005216 | IEA | InterPro | ion channel activity | |
GO:0015079 | IEA | PLAZA Homology | potassium ion transmembrane transporter activity | HOM03M000275 |
GO:0022843 | IEA | PLAZA Homology | voltage-gated cation channel activity | HOM03M000275 |
GO:0022803 | IEA | PLAZA Homology | passive transmembrane transporter activity | HOM03M000275 |
GO:0022839 | IEA | PLAZA Homology | ion gated channel activity | HOM03M000275 |
GO:0005244 | IEA | PLAZA Homology | voltage-gated ion channel activity | HOM03M000275 |
GO:0005261 | IEA | PLAZA Homology | cation channel activity | HOM03M000275 |
GO:0022836 | IEA | PLAZA Homology | gated channel activity | HOM03M000275 |
GO:0022838 | IEA | PLAZA Homology | substrate-specific channel activity | HOM03M000275 |
GO:0022832 | IEA | PLAZA Homology | voltage-gated channel activity | HOM03M000275 |
GO:0005267 | IEA | PLAZA Homology | potassium channel activity | HOM03M000275 |
GO:0015267 | IEA | PLAZA Homology | channel activity | HOM03M000275 |
Cellular Component
GO term | Evidence(s) | Provider | Description | Source |
---|---|---|---|---|
GO:0009506 | IDA | UniProt | plasmodesma | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 |
GO:0005789 | IEA | UniProt | endoplasmic reticulum membrane | 1 2 3 4 5 6 7 8 9 10 11 12 13 |
GO:0016021 | IEA | UniProt | integral to membrane | 1 2 3 4 5 6 7 8 9 10 11 12 13 |
GO:0016020 | IEA | InterPro | membrane |
Color Legend
Experimental Evidence |
Electronic Evidence |
Computational Reviewed Evidence |
InterPro | Description |
---|---|
IPR003938 | Potassium channel, voltage-dependent, EAG/ELK/ERG |
IPR002110 | Ankyrin repeat |
IPR000595 | Cyclic nucleotide-binding domain |
IPR020683 | Ankyrin repeat-containing domain |
IPR014710 | RmlC-like jelly roll fold |
IPR005821 | Ion transport domain |
IPR021789 | Potassium channel, plant-type |
IPR018490 | Cyclic nucleotide-binding-like |
Mapman id | Description |
---|---|
34.15 | transport.potassium |
No SignalP domains detected for this gene.