Gene: AT4G19710 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G19710
Transcript Identifier
AT4G19710.2
Gene Type
Coding gene
Location
4 : 10725229-10729536 : positive

Family

Gene family
HOM03M001448
(53 genes in 16 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
aspartate kinase-homoserine dehydrogenase ii
Curated Summary
Encodes a bifunctional aspartate kinase/homoserine dehydrogenase. These two activities catalyze the first and the third steps toward the synthesis of the essential amino acids threonine, isoleucine and methionine.
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Identifiers

Identifier Name
aliasASPARTATE KINASE-HOMOSERINE DEHYDROGENASE
aliasAK-HSDH
aliasAK-HSDH II
aliasaspartate kinase-homoserine dehydrogenase ii
uniprotO81852

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006164RCAGene Ontologypurine nucleotide biosynthetic process1
GO:0009067TASGene Ontologyaspartate family amino acid biosynthetic process1
GO:0009089IEAUniProtlysine biosynthetic process via diaminopimelate1 2 3 4 5
GO:0009086IEAUniProtmethionine biosynthetic process1 2 3 4 5
GO:0009088IEAUniProtthreonine biosynthetic process1 2 3 4 5
GO:0006520IEAInterProcellular amino acid metabolic process
GO:0008152IEAInterPrometabolic process
GO:0008652IEAInterProcellular amino acid biosynthetic process
GO:0055114IEAInterProoxidation-reduction process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004072IDA, IEA, UniProtaspartate kinase activity1 2 3 4 5 6
GO:0004412IDAUniProthomoserine dehydrogenase activity1 2 3 4 5 6
GO:0016597IEAUniProtamino acid binding1 2 3 4 5
GO:0005524IEAUniProtATP binding1 2 3 4 5
GO:0050661IEAUniProtNADP binding1 2 3 4 5
GO:0016491IEAInterProoxidoreductase activity

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507IDA, ISMGene Ontologychloroplast1 2
GO:0009570IDAUniProtchloroplast stroma1 2 3 4 5 6

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002912ACT domain
IPR001342Homoserine dehydrogenase, catalytic
IPR001341Aspartate kinase domain
IPR001048Aspartate/glutamate/uridylate kinase
IPR016040NAD(P)-binding domain
IPR005106Aspartate/homoserine dehydrogenase, NAD-binding
IPR018042Aspartate kinase, conserved site
IPR019811Homoserine dehydrogenase, conserved site

Mapman id Description
13.1.3.6.1.10amino acid metabolism.synthesis.aspartate family.misc.homoserine.bifunctional aspartate kinase/homoserine dehydrogenase
No SignalP domains detected for this gene.