Gene: AT4G17380 (Arabidopsis thaliana)

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Gene Identifier
AT4G17380
Transcript Identifier
AT4G17380.1
Gene Type
Coding gene
Location
4 : 9708742-9714068 : positive

Family

Gene family
HOM03M003228
(27 genes in 14 species)
specific family
Subfamily
ORTHO03M011524
(4 genes in 4 species)
specific family

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Descriptions

Description
MUTS-like protein 4
Curated Summary
Encodes the Arabidopsis homolog of MSH4, a meiosis-specific member of the MutS-homolog family of genes. It is expressed only in floral tissues and only during early meiotic prophase I, preceding the synapsis of homologous chromosomes. It is involved in the early steps of recombination.
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Identifiers

Identifier Name
aliasMUTS HOMOLOG 4
aliasARABIDOPSIS MUTS HOMOLOG 4
aliasMSH4
aliasMUTS-like protein 4
aliasATMSH4
uniprotF4JP48

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0000710IBAGene Ontologymeiotic mismatch repair1
GO:0006200IBAGene OntologyATP catabolic process1
GO:0006298ISS, IEAGene Ontologymismatch repair1
GO:0007131IBA, RCAGene Ontologyreciprocal meiotic recombination1 2
GO:0045143IMP, IBAUniProthomologous chromosome segregation1 2 3 4 5 6 7 8
GO:0051026IBAUniProtchiasma assembly1 2 3 4 5 6 7 8
GO:0007129IMP, RCAGene Ontologysynapsis1 2
GO:0000911RCAGene Ontologycytokinesis by cell plate formation1
GO:0006302RCAGene Ontologydouble-strand break repair1
GO:0006312RCAGene Ontologymitotic recombination1
GO:0007059RCAGene Ontologychromosome segregation1
GO:0007062RCAGene Ontologysister chromatid cohesion1
GO:0007067RCAGene Ontologymitosis1
GO:0007126RCAGene Ontologymeiosis1
GO:0010332RCAGene Ontologyresponse to gamma radiation1
GO:0010564RCAGene Ontologyregulation of cell cycle process1
GO:0032204RCAGene Ontologyregulation of telomere maintenance1
GO:0032504RCAGene Ontologymulticellular organism reproduction1
GO:0042138RCAGene Ontologymeiotic DNA double-strand break formation1
GO:0043247RCAGene Ontologytelomere maintenance in response to DNA damage1
GO:0045132RCAGene Ontologymeiotic chromosome segregation1
GO:0010777IMPUniProtmeiotic mismatch repair involved in reciprocal meiotic recombination1 2 3 4 5 6 7

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003684IBA, ISS, UniProtdamaged DNA binding1 2 3 4 5 6 7 8 9
GO:0005524IEA, ISSUniProtATP binding1 2 3 4 5 6 7 8
GO:0008094IBAUniProtDNA-dependent ATPase activity1 2 3 4 5 6 7 8
GO:0030983IBA, IEA, UniProtmismatched DNA binding1 2 3 4 5 6 7 8

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0000795IBAUniProtsynaptonemal complex1 2 3 4 5 6 7 8
GO:0005634ISMGene Ontologynucleus1
GO:0032300IBAUniProtmismatch repair complex1 2 3 4 5 6 7 8
GO:0000794IDAGene Ontologycondensed nuclear chromosome1
GO:0009506IDAUniProtplasmodesma1 2 3 4 5 6 7 8
GO:0043073IDAUniProtgerm cell nucleus1 2 3 4 5 6 7

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000432DNA mismatch repair protein MutS, C-terminal
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR007696DNA mismatch repair protein MutS, core
IPR007861DNA mismatch repair protein MutS, clamp

Mapman id Description
28.2DNA.repair
No SignalP domains detected for this gene.