Gene: AT4G15900 (Arabidopsis thaliana)

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Gene Identifier
AT4G15900
Transcript Identifier
AT4G15900.1
Gene Type
Coding gene
Location
4 : 9023775-9027443 : positive

Family

Gene family
HOM03M000141
(335 genes in 16 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
pleiotropic regulatory locus 1
Curated Summary
Mutations confer hypersensitivity to glucose and sucrose and augments sensitivity to cytokinin, ethylene, ABA and auxin. Encodes a nuclear WD40 protein that is imported into the nucleus. Essential for plant innate immunity. Interacts with MOS4 and AtCDC5. It is also predicted to have two DWD motifs. It can bind to DDB1a in Y2H assays, and DDB1b in co-IP assays, and may be involved in the formation of a CUL4-based E3 ubiquitin ligase, and may affect the stability of AKIN10.
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Identifiers

Identifier Name
aliasPRL1
aliaspleiotropic regulatory locus 1
uniprotQ42384

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0045892IMPUniProtnegative regulation of transcription, DNA-dependent1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0009870IMPUniProtdefense response signaling pathway, resistance gene-dependent1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0010204IMPUniProtdefense response signaling pathway, resistance gene-independent1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0042742IMPUniProtdefense response to bacterium1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0050832IMPUniProtdefense response to fungus1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0006508IMPUniProtproteolysis1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0009755IMP, RCA, UniProthormone-mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0010154IMPGene Ontologyfruit development1
GO:0010182IMP, RCA, UniProtsugar mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0048364IMPUniProtroot development1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0048366IMP, RCAGene Ontologyleaf development1 2
GO:0048825IMP, RCA, UniProtcotyledon development1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0000278RCAGene Ontologymitotic cell cycle1
GO:0006355RCAGene Ontologyregulation of transcription, DNA-dependent1
GO:0006396RCAGene OntologyRNA processing1
GO:0007062RCAGene Ontologysister chromatid cohesion1
GO:0009640RCAGene Ontologyphotomorphogenesis1
GO:0009793RCAGene Ontologyembryo development ending in seed dormancy1
GO:0009845RCAGene Ontologyseed germination1
GO:0009880RCAGene Ontologyembryonic pattern specification1
GO:0009909RCAGene Ontologyregulation of flower development1
GO:0009933RCAGene Ontologymeristem structural organization1
GO:0010072RCAGene Ontologyprimary shoot apical meristem specification1
GO:0010162RCAGene Ontologyseed dormancy process1
GO:0010228RCAGene Ontologyvegetative to reproductive phase transition of meristem1
GO:0010431RCAGene Ontologyseed maturation1
GO:0010564RCAGene Ontologyregulation of cell cycle process1
GO:0016567IEA, RCAUniProtprotein ubiquitination1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0019915RCAGene Ontologylipid storage1
GO:0043687RCAGene Ontologypost-translational protein modification1
GO:0045595RCAGene Ontologyregulation of cell differentiation1
GO:0045893RCAGene Ontologypositive regulation of transcription, DNA-dependent1
GO:0050826RCAGene Ontologyresponse to freezing1
GO:0051301RCAGene Ontologycell division1
GO:0009749IMPUniProtresponse to glucose1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0045087IEAUniProtinnate immune response1 2 3 4 5 6 7 8 9 10 11 12

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0000166ISSGene Ontologynucleotide binding1
GO:0005515IPI, IEAGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISM, UniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0080008IPIUniProtCul4-RING ubiquitin ligase complex1 2 3 4 5 6 7 8 9 10 11 12 13

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001680WD40 repeat
IPR017986WD40-repeat-containing domain
IPR019775WD40 repeat, conserved site
IPR020472G-protein beta WD-40 repeat
IPR015943WD40/YVTN repeat-like-containing domain

Mapman id Description
30.1signalling.in sugar and nutrient physiology
No SignalP domains detected for this gene.