Gene: AT4G14220 (Arabidopsis thaliana)

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Gene Identifier
AT4G14220
Transcript Identifier
AT4G14220.1
Gene Type
Coding gene
Location
4 : 8196012-8198240 : positive

Family

Gene family
HOM03M001720
(45 genes in 14 species)
specific family
Subfamily
ORTHO03M011516
(4 genes in 4 species)
specific family

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Descriptions

Description
RING-H2 group F1A
Curated Summary
encodes a RING-type E3 ubiquitin ligase implicated in gametogenesis. RHF1a can interact with the cell cycle inhibitor ICK4/KRP6 in vitro. It apppears to target ICK4KRP6 for degradation following meiosis in order to allow the mitoses associated with megagametogenesis and microgametogenesis to occur. RHF1a is expressed in the carpels throughout floral development. It is expressed in various tissues of the anthers during the early stages of anther development but not in stage 12 flowers and beyond.
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Identifiers

Identifier Name
aliasRING-H2 group F1A
aliasRHF1A
uniprotQ4TU14

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009561IGIUniProtmegagametogenesis1 2 3 4 5 6
GO:0010498IDAUniProtproteasomal protein catabolic process1 2 3 4 5 6
GO:0016567IDAGene Ontologyprotein ubiquitination1
GO:0051726IGIUniProtregulation of cell cycle1 2 3 4 5 6
GO:0055046IGIUniProtmicrogametogenesis1 2 3 4 5 6
GO:0000165RCAGene OntologyMAPK cascade1
GO:0006355RCAGene Ontologyregulation of transcription, DNA-dependent1
GO:0006612RCAGene Ontologyprotein targeting to membrane1
GO:0009617RCAGene Ontologyresponse to bacterium1
GO:0009862RCAGene Ontologysystemic acquired resistance, salicylic acid mediated signaling pathway1
GO:0009867RCAGene Ontologyjasmonic acid mediated signaling pathway1
GO:0010310RCAGene Ontologyregulation of hydrogen peroxide metabolic process1
GO:0010363RCAGene Ontologyregulation of plant-type hypersensitive response1
GO:0031348RCAGene Ontologynegative regulation of defense response1
GO:0035304RCAGene Ontologyregulation of protein dephosphorylation1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008270IEA, ISSUniProtzinc ion binding1 2 3 4 5 6
GO:0004842IDAUniProtubiquitin-protein ligase activity1 2 3 4 5 6
GO:0005515IPI, IEAGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1
GO:0016020IDAUniProtmembrane1 2 3 4 5 6

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001841Zinc finger, RING-type
IPR013083Zinc finger, RING/FYVE/PHD-type

Mapman id Description
29.5.11.4.2protein.degradation.ubiquitin.E3.RING
No SignalP domains detected for this gene.