Gene: AT4G02570 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT4G02570
Transcript Identifier
AT4G02570.1
Gene Type
Coding gene
Location
4 : 1129315-1133435 : positive

Family

Gene family
HOM03M000391
(156 genes in 16 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
cullin 1
Curated Summary
Encodes a cullin that is a component of SCF ubiquitin ligase complexes involved in mediating responses to auxin and jasmonic acid. Homozygous auxin-resistant mutants arrest growth soon after germination, lacking a root and hypocotyl. Heterozygotes display a variety of phenotypes consistent with impaired auxin response.
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Identifiers

Identifier Name
aliasAXR6
aliascullin 1
aliasAUXIN RESISTANT 6
aliasATCUL1
aliasCUL1
uniprotQ94AH6

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009733IMPUniProtresponse to auxin1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0009793IMPUniProtembryo development ending in seed dormancy1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0009753IMPGene Ontologyresponse to jasmonic acid1
GO:0009867TASUniProtjasmonic acid mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0010265IPIUniProtSCF complex assembly1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0042752IMP, RCA, UniProtregulation of circadian rhythm1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0000278RCAGene Ontologymitotic cell cycle1
GO:0006396RCAGene OntologyRNA processing1
GO:0006486RCAGene Ontologyprotein glycosylation1
GO:0006499RCAGene OntologyN-terminal protein myristoylation1
GO:0006511IEA, RCAUniProtubiquitin-dependent protein catabolic process1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0006888RCAGene OntologyER to Golgi vesicle-mediated transport1
GO:0007062RCAGene Ontologysister chromatid cohesion1
GO:0009790RCAGene Ontologyembryo development1
GO:0009880RCAGene Ontologyembryonic pattern specification1
GO:0010072RCAGene Ontologyprimary shoot apical meristem specification1
GO:0010162RCAGene Ontologyseed dormancy process1
GO:0010431RCAGene Ontologyseed maturation1
GO:0010564RCAGene Ontologyregulation of cell cycle process1
GO:0043090RCAGene Ontologyamino acid import1
GO:0045595RCAGene Ontologyregulation of cell differentiation1
GO:0048316RCAGene Ontologyseed development1
GO:0048366IMP, RCA, UniProtleaf development1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0048825RCAGene Ontologycotyledon development1
GO:0051301RCAGene Ontologycell division1
GO:0010087IMPUniProtphloem or xylem histogenesis1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0009734IEAUniProtauxin mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12
GO:0007049IEAUniProtcell cycle1 2 3 4 5 6 7 8 9 10 11 12
GO:0009873IEAUniProtethylene mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12
GO:0016567IEAUniProtprotein ubiquitination1 2 3 4 5 6 7 8 9 10 11 12
GO:0044265IEAPLAZA Homologycellular macromolecule catabolic processHOM03M000391
GO:0030163IEAPLAZA Homologyprotein catabolic processHOM03M000391
GO:0051603IEAPLAZA Homologyproteolysis involved in cellular protein catabolic processHOM03M000391
GO:0019941IEAPLAZA Homologymodification-dependent protein catabolic processHOM03M000391
GO:0044257IEAPLAZA Homologycellular protein catabolic processHOM03M000391
GO:0043632IEAPLAZA Homologymodification-dependent macromolecule catabolic processHOM03M000391

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005515IPIGene Ontologyprotein binding1
GO:0031625IEAInterProubiquitin protein ligase binding
GO:0044389IEAPLAZA Homologysmall conjugating protein ligase bindingHOM03M000391
GO:0019899IEAPLAZA Homologyenzyme bindingHOM03M000391

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISMGene Ontologynucleus1 2
GO:0000151IPIUniProtubiquitin ligase complex1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0005819IDAUniProtspindle1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0009524IDAUniProtphragmoplast1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0000794IDAUniProtcondensed nuclear chromosome1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0005737IDAGene Ontologycytoplasm1
GO:0005829IDAUniProtcytosol1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0031461IEAUniProtcullin-RING ubiquitin ligase complex1 2 3 4 5 6 7 8 9 10 11 12

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR016158Cullin homology
IPR016159Cullin repeat-like-containing domain
IPR019559Cullin protein, neddylation domain
IPR011991Winged helix-turn-helix DNA-binding domain
IPR016157Cullin, conserved site
IPR001373Cullin, N-terminal

Mapman id Description
29.5.11.4.3.3protein.degradation.ubiquitin.E3.SCF.cullin
No SignalP domains detected for this gene.