Gene: AT4G02460 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
4 : 1076306-1080510 : negative


Gene family
(19 genes in 16 species)
specific family

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DNA mismatch repair protein, putative
Curated Summary
Encodes a protein similar to PMS1 in yeast, a member of the family of eukaryotic MutL homologs. The protein appears to play a role in DNA mismatch repair and in the suppression of somatic homeologous recombination.
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Identifier Name





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006200IBAGene OntologyATP catabolic process1
GO:0006298IMP, ISSIEA, UniProtmismatch repair1 2 3 4 5 6 7 8
GO:0007131IBA, RCA, UniProtreciprocal meiotic recombination1 2 3 4 5 6 7 8
GO:0006310IMPGene OntologyDNA recombination1
GO:0009555IMP, RCA, UniProtpollen development1 2 3 4 5 6 7 8
GO:0010154IMPGene Ontologyfruit development1
GO:0048316IMPUniProtseed development1 2 3 4 5 6 7
GO:0000278RCAGene Ontologymitotic cell cycle1
GO:0000724RCAGene Ontologydouble-strand break repair via homologous recombination1
GO:0006261RCAGene OntologyDNA-dependent DNA replication1
GO:0006275RCAGene Ontologyregulation of DNA replication1
GO:0006306RCAGene OntologyDNA methylation1
GO:0006312RCAGene Ontologymitotic recombination1
GO:0006355RCAGene Ontologyregulation of transcription, DNA-dependent1
GO:0007062RCAGene Ontologysister chromatid cohesion1
GO:0007129RCAGene Ontologysynapsis1
GO:0007140RCAGene Ontologymale meiosis1
GO:0007267RCAGene Ontologycell-cell signaling1
GO:0009560RCAGene Ontologyembryo sac egg cell differentiation1
GO:0009616RCAGene Ontologyvirus induced gene silencing1
GO:0009640RCAGene Ontologyphotomorphogenesis1
GO:0009691RCAGene Ontologycytokinin biosynthetic process1
GO:0009793RCAGene Ontologyembryo development ending in seed dormancy1
GO:0009845RCAGene Ontologyseed germination1
GO:0009880RCAGene Ontologyembryonic pattern specification1
GO:0009909RCAGene Ontologyregulation of flower development1
GO:0009933RCAGene Ontologymeristem structural organization1
GO:0010050RCAGene Ontologyvegetative phase change1
GO:0010072RCAGene Ontologyprimary shoot apical meristem specification1
GO:0010162RCAGene Ontologyseed dormancy process1
GO:0010182RCAGene Ontologysugar mediated signaling pathway1
GO:0010228RCAGene Ontologyvegetative to reproductive phase transition of meristem1
GO:0010267RCAGene Ontologyproduction of ta-siRNAs involved in RNA interference1
GO:0010431RCAGene Ontologyseed maturation1
GO:0010564RCAGene Ontologyregulation of cell cycle process1
GO:0016444RCAGene Ontologysomatic cell DNA recombination1
GO:0016567RCAGene Ontologyprotein ubiquitination1
GO:0016568RCAGene Ontologychromatin modification1
GO:0019915RCAGene Ontologylipid storage1
GO:0031047RCAGene Ontologygene silencing by RNA1
GO:0035196RCAGene Ontologyproduction of miRNAs involved in gene silencing by miRNA1
GO:0043687RCAGene Ontologypost-translational protein modification1
GO:0045595RCAGene Ontologyregulation of cell differentiation1
GO:0045893RCAGene Ontologypositive regulation of transcription, DNA-dependent1
GO:0048366RCAGene Ontologyleaf development1
GO:0048825RCAGene Ontologycotyledon development1
GO:0050826RCAGene Ontologyresponse to freezing1
GO:0051301RCAGene Ontologycell division1
GO:0051726RCAGene Ontologyregulation of cell cycle1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005524IEA, ISSUniProtATP binding1 2 3 4 5 6 7
GO:0016887IBAUniProtATPase activity1 2 3 4 5 6 7
GO:0030983IBA, IEA, UniProtmismatched DNA binding1 2 3 4 5 6 7

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IC, ISMGene Ontologynucleus1 2
GO:0032389IBA, IEA, UniProtMutLalpha complex1 2 3 4 5 6 7

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR013507DNA mismatch repair protein, C-terminal
IPR002099DNA mismatch repair protein family
IPR003594Histidine kinase-like ATPase, ATP-binding domain
IPR015434DNA mismatch repair protein Pms1/Mlh2
IPR014790MutL, C-terminal, dimerisation
IPR014721Ribosomal protein S5 domain 2-type fold, subgroup
IPR014762DNA mismatch repair, conserved site
IPR020568Ribosomal protein S5 domain 2-type fold

Mapman id Description
No SignalP domains detected for this gene.