Gene: AT3G62980 (Arabidopsis thaliana)

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Gene Identifier
AT3G62980
Transcript Identifier
AT3G62980.1
Gene Type
Coding gene
Location
3 : 23273479-23276181 : negative

Family

Gene family
HOM03M000440
(144 genes in 14 species)
specific family

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Descriptions

Description
F-box/RNI-like superfamily protein
Curated Summary
Encodes an auxin receptor that mediates auxin-regulated transcription. It contains leucine-rich repeats and an F-box and interacts with ASK1, ASK2 and AtCUL1 to form SCF-TIR1, an SCF ubiquitin ligase complex. Related to yeast Grr1p and human SKP2 proteins, involved in ubiquitin-mediated processes. Required for normal response to auxin and repressed in response to flagellin. As part of the SCF complex and in the presence of auxin, TIR1 interacts with Aux/IAA transcriptional repressor proteins and mediates their degradation. Mutations in TIR1 block auxin stimulation of flavonoid synthesis.
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Identifiers

Identifier Name
aliasAtTIR1
aliasTIR1
aliasTRANSPORT INHIBITOR RESPONSE 1
uniprotQ570C0

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006511RCA, TASGene Ontologyubiquitin-dependent protein catabolic process1 2
GO:0002237IEP, RCA, UniProtresponse to molecule of bacterial origin1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0009734IMPUniProtauxin mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0010152IGIUniProtpollen maturation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0048443IGI, RCA, UniProtstamen development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0016036IEPUniProtcellular response to phosphate starvation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0007165RCAGene Ontologysignal transduction1
GO:0010103RCAGene Ontologystomatal complex morphogenesis1
GO:0042752RCAGene Ontologyregulation of circadian rhythm1
GO:0009733IMPGene Ontologyresponse to auxin1
GO:0010311IMPUniProtlateral root formation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0007049IEAUniProtcell cycle1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0006952IEAUniProtdefense response1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0009873IEAUniProtethylene mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004842IC, ISS, UniProtubiquitin-protein ligase activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0010011IDA, IGI, UniProtauxin binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
GO:0000822IDAUniProtinositol hexakisphosphate binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IEA, ISMUniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0000151IDAGene Ontologyubiquitin ligase complex1
GO:0019005IDAUniProtSCF ubiquitin ligase complex1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006553Leucine-rich repeat, cysteine-containing subtype
IPR001810F-box domain

Mapman id Description
17.2.2hormone metabolism.auxin.signal transduction
No SignalP domains detected for this gene.