Gene: AT3G54470 (Arabidopsis thaliana)

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Gene Identifier
AT3G54470
Transcript Identifier
AT3G54470.1
Gene Type
Coding gene
Location
3 : 20168285-20170245 : negative

Family

Gene family
HOM03M002313
(36 genes in 16 species)
specific family

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Descriptions

Description
uridine 5'-monophosphate synthase / UMP synthase (PYRE-F) (UMPS)
Curated Summary
encodes the bi-functional orotate phosphoribosyltransferase/orotidine-5'-phosphate decarboxylase catalyzing the fifth and sixth step in the de novo pyrimidine ribonucleotide biosynthesis
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Identifiers

Identifier Name
uniprotQ42586

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009116ISS, IEAGene Ontologynucleoside metabolic process1
GO:0016036IEPUniProtcellular response to phosphate starvation1 2 3 4
GO:0046686IEPUniProtresponse to cadmium ion1 2 3 4
GO:0009220IGIUniProtpyrimidine ribonucleotide biosynthetic process1 2 3 4
GO:0006207IEAUniProt'de novo' pyrimidine nucleobase biosynthetic process1 2 3
GO:0044205IEAUniProt'de novo' UMP biosynthetic process1 2 3
GO:0008152IEAInterPrometabolic process
GO:0006221IEAInterPropyrimidine nucleotide biosynthetic process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004588IGI, ISSIEA, UniProtorotate phosphoribosyltransferase activity1 2 3 4 5
GO:0004590IGI, ISSIEA, UniProtorotidine-5'-phosphate decarboxylase activity1 2 3 4 5
GO:0003824IEAInterProcatalytic activity

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1
GO:0005829IDAUniProtcytosol1 2 3 4

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011060Ribulose-phosphate binding barrel
IPR023031Orotate phosphoribosyltransferase
IPR001754Orotidine 5'-phosphate decarboxylase domain
IPR014732Orotidine 5'-phosphate decarboxylase
IPR013785Aldolase-type TIM barrel
IPR000836Phosphoribosyltransferase domain
IPR018089Orotidine 5'-phosphate decarboxylase, active site
IPR004467Orotate phosphoribosyl transferase domain

Mapman id Description
23.1.1.5nucleotide metabolism.synthesis.pyrimidine.orotate phosphoribosyltransferase
No SignalP domains detected for this gene.