Gene: AT3G25980 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G25980
Transcript Identifier
AT3G25980.1
Gene Type
Coding gene
Location
3 : 9503232-9504402 : positive

Family

Gene family
HOM03M005726
(18 genes in 16 species)
specific family

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Descriptions

Description
DNA-binding HORMA family protein
Curated Summary
Encodes MAD2 (MITOTIC ARREST-DEFICIENT 2). May have the spindle assembly checkpoint protein functions conserved from yeast to humans.
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Identifiers

Identifier Name
aliasMITOTIC ARREST-DEFICIENT 2
aliasAtMAD2
aliasMAD2
uniprotQ9LU93

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007094IDA, ISSIEA, UniProtmitotic spindle assembly checkpoint1 2 3 4 5
GO:0007346IMPGene Ontologyregulation of mitotic cell cycle1
GO:0008283RCAGene Ontologycell proliferation1
GO:0016572RCAGene Ontologyhistone phosphorylation1
GO:0042023RCAGene OntologyDNA endoreduplication1
GO:0043161RCAGene Ontologyproteasome-mediated ubiquitin-dependent protein catabolic process1
GO:0043248RCAGene Ontologyproteasome assembly1
GO:0051510RCAGene Ontologyregulation of unidimensional cell growth1
GO:0051788RCAGene Ontologyresponse to misfolded protein1
GO:0009555IMPGene Ontologypollen development1
GO:0048235IMPGene Ontologypollen sperm cell differentiation1
GO:0051301IEAUniProtcell division1 2 3
GO:0007067IEAUniProtmitosis1 2 3
GO:0031577IEAPLAZA Homologyspindle checkpointHOM03M005726
GO:0071173IEAPLAZA Homologyspindle assembly checkpointHOM03M005726
GO:0071174IEAPLAZA Homologymitotic spindle checkpointHOM03M005726

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003677ISSGene OntologyDNA binding1
GO:0005515IPIGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISMGene Ontologynucleus1 2
GO:0000776IDAUniProtkinetochore1 2 3 4
GO:0010369IDAUniProtchromocenter1 2 3 4
GO:0005635IDAUniProtnuclear envelope1 2 3 4
GO:0005737IDAUniProtcytoplasm1 2 3 4
GO:0000777IEAUniProtcondensed chromosome kinetochore1 2 3
GO:0005828IDAUniProtkinetochore microtubule1 2 3

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003511DNA-binding HORMA
IPR027097Mitotic spindle checkpoint protein Mad2

Mapman id Description
31.2cell.division
No SignalP domains detected for this gene.