Gene: AT3G21230 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G21230
Transcript Identifier
AT3G21230.1
Gene Type
Coding gene
Location
3 : 7448231-7451947 : negative

Family

Gene family
HOM03M000192
(259 genes in 14 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

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Descriptions

Description
4-coumarate:CoA ligase 5
Curated Summary
The gene encodes a 4-coumarate coenzyme A ligase being able to use sinapate as substrate. The catalytic efficiency was in the following (descending) order: p-coumaric acid, caffeic acid, 5-OH-ferulic acid, ferulic acid and sinapic acid. At4CL5 was unable to use cinnamic acid as substrate. Knockout of At4CL5 (4cl5) revealed no effect on syringyl lignin content indicating that the activity observed does probably not occur in vivo.
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Identifiers

Identifier Name
alias4-coumarate:CoA ligase 5
alias4CL5
uniprotQ9LU36

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009699IDAUniProtphenylpropanoid biosynthetic process1 2 3 4 5 6 7
GO:0009611RCAGene Ontologyresponse to wounding1
GO:0009805RCAGene Ontologycoumarin biosynthetic process1
GO:0009963RCAGene Ontologypositive regulation of flavonoid biosynthetic process1
GO:0052542RCAGene Ontologydefense response by callose deposition1
GO:0008152IEAInterPrometabolic process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016207IDAUniProt4-coumarate-CoA ligase activity1 2 3 4 5 6 7
GO:0005524IEAUniProtATP binding1 2 3 4 5 6
GO:0003824IEAInterProcatalytic activity

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR020845AMP-binding, conserved site
IPR000873AMP-dependent synthetase/ligase
IPR025110AMP-binding enzyme C-terminal domain

Mapman id Description
16.2.1.3secondary metabolism.phenylpropanoids.lignin biosynthesis.4CL
No SignalP domains detected for this gene.