Gene: AT3G19760 (Arabidopsis thaliana)

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Gene Identifier
AT3G19760
Transcript Identifier
AT3G19760.1
Gene Type
Coding gene
Location
3 : 6863790-6866242 : positive

Family

Gene family
HOM03M000037
(943 genes in 16 species)
specific family

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Descriptions

Description
eukaryotic initiation factor 4A-III
Curated Summary
Encodes an RNA helicase that may be a component of the Exon Junction Complex. Subcellular localization is modulated by stress. Under normal conditions it is localized to the nuceloplasm but under hyopoxic conditions it localizes to the nucleolus and splicing speckles.
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Identifiers

Identifier Name
aliaseukaryotic initiation factor 4A-III
aliasEIF4A-III
uniprotQ94A52

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0001666IDAUniProtresponse to hypoxia1 2 3 4 5
GO:0006397IPIUniProtmRNA processing1 2 3 4 5
GO:0006364IEAUniProtrRNA processing1 2 3 4

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008026IEA, ISSUniProtATP-dependent helicase activity1 2 3 4 5
GO:0005515IPIGene Ontologyprotein binding1
GO:0005524IEAUniProtATP binding1 2 3 4
GO:0003723IEAUniProtRNA binding1 2 3 4
GO:0004386IEAInterProhelicase activity
GO:0003676IEAInterPronucleic acid binding
GO:0032555IEAPLAZA Homologypurine ribonucleotide bindingHOM03M000037
GO:0016817IEAPLAZA Homologyhydrolase activity, acting on acid anhydridesHOM03M000037
GO:0043168IEAPLAZA Homologyanion bindingHOM03M000037
GO:0042623IEAPLAZA HomologyATPase activity, coupledHOM03M000037
GO:0032553IEAPLAZA Homologyribonucleotide bindingHOM03M000037
GO:0043167IEAPLAZA Homologyion bindingHOM03M000037
GO:0035639IEAPLAZA Homologypurine ribonucleoside triphosphate bindingHOM03M000037
GO:0097367IEAPLAZA Homologycarbohydrate derivative bindingHOM03M000037
GO:0003824IEAPLAZA Homologycatalytic activityHOM03M000037
GO:0016818IEAPLAZA Homologyhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesHOM03M000037
GO:0032559IEAPLAZA Homologyadenyl ribonucleotide bindingHOM03M000037
GO:1901265IEAPLAZA Homologynucleoside phosphate bindingHOM03M000037
GO:0016462IEAPLAZA Homologypyrophosphatase activityHOM03M000037
GO:0000166IEAPLAZA Homologynucleotide bindingHOM03M000037
GO:0030554IEAPLAZA Homologyadenyl nucleotide bindingHOM03M000037
GO:0001882IEAPLAZA Homologynucleoside bindingHOM03M000037
GO:0097159IEAPLAZA Homologyorganic cyclic compound bindingHOM03M000037
GO:0017076IEAPLAZA Homologypurine nucleotide bindingHOM03M000037
GO:0016887IEAPLAZA HomologyATPase activityHOM03M000037
GO:0017111IEAPLAZA Homologynucleoside-triphosphatase activityHOM03M000037
GO:0036094IEAPLAZA Homologysmall molecule bindingHOM03M000037
GO:0032549IEAPLAZA Homologyribonucleoside bindingHOM03M000037
GO:0016787IEAPLAZA Homologyhydrolase activityHOM03M000037
GO:1901363IEAPLAZA Homologyheterocyclic compound bindingHOM03M000037
GO:0005488IEAPLAZA HomologybindingHOM03M000037
GO:0001883IEAPLAZA Homologypurine nucleoside bindingHOM03M000037
GO:0032550IEAPLAZA Homologypurine ribonucleoside bindingHOM03M000037
GO:0070035IEAPLAZA Homologypurine NTP-dependent helicase activityHOM03M000037

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISMGene Ontologynucleus1 2
GO:0005730IDAUniProtnucleolus1 2 3 4 5
GO:0016020IDAUniProtmembrane1 2 3 4 5
GO:0005654IDAGene Ontologynucleoplasm1
GO:0016607IDAUniProtnuclear speck1 2 3 4 5
GO:0035145IDAUniProtexon-exon junction complex1 2 3 4 5

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR014001Helicase, superfamily 1/2, ATP-binding domain
IPR011545DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR014014RNA helicase, DEAD-box type, Q motif
IPR001650Helicase, C-terminal
IPR027417P-loop containing nucleoside triphosphate hydrolase

Mapman id Description
29.2.2.3.5protein.synthesis.ribosome biogenesis.Pre-rRNA processing and modifications.DExD-box helicases
No SignalP domains detected for this gene.