Gene: AT3G19150 (Arabidopsis thaliana)

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Gene Identifier
AT3G19150
Transcript Identifier
AT3G19150.1
Gene Type
Coding gene
Location
3 : 6616628-6617655 : negative

Family

Gene family
HOM03M001074
(68 genes in 13 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
KIP-related protein 6
Curated Summary
Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. Binds to D type cyclins. A member of seven KRP genes found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization. KRP6 appears to be targeted for degradation by RHF1a and RHF2a to allow mitotic divisions during gametogenesis. In addition, KRP6 transcript levels rise prior to and drop following the meitotic divisions of gametogenesis. Elevated levels of KRP6 negatively affect plant development and fertility.
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Identifiers

Identifier Name
aliasAtKRP6
aliasICK4
aliasKIP-related protein 6
aliasACK1
aliasKRP6
aliasARABIDOPSIS CDK INHIBITOR 1
uniprotQ0WNX9

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0042023IMPGene OntologyDNA endoreduplication1 AGRICOLA_IND:IND23305253
GO:0045736IDA, TAS, UniProtnegative regulation of cyclin-dependent protein serine/threonine kinase activity1 AGRICOLA_IND:IND233052532 3 4 5 6 7 8 9 10 11
GO:0007050IEAUniProtcell cycle arrest1 2 3 4 5 6 7 8 9

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004861IEA, TASUniProtcyclin-dependent protein serine/threonine kinase inhibitor activity1 AGRICOLA_IND:IND233052532 3 4 5 6 7 8 9 10
GO:0030332IPIGene Ontologycyclin binding1 AGRICOLA_IND:IND23305253
GO:0005515IPIGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISM, IEAGene Ontologynucleus1
GO:0001673IDAUniProtmale germ cell nucleus1 2 3 4 5 6 7 8 9 10
GO:0005654IEAUniProtnucleoplasm1 2 3 4 5 6 7 8 9

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003175Cyclin-dependent kinase inhibitor

Mapman id Description
31.3cell.cycle
No SignalP domains detected for this gene.