PLAZA 3.0 Monocots gene overview : AT3G12400

Gene: AT3G12400 (Arabidopsis thaliana)

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Curated Summary: Mutants of this gene were initially identified because of the trichome morphogenesis phenotype. Those trichomes have multiple nuclei, a defect that turns out not to be restricted to the trichomes but also in all endoreduplicating cell types. This gene encodes a ubiquitin-binding protein with sequence similarities with yeast proteins that are components of the ESCRTI-III complexes. The Arabidopsis protein is found associated with the endosome.

GO term	Evidence(s)	Provider	Description	Source
GO:0010091	IMP	UniProt	trichome branching	1 2 3 4 5 6
GO:0051301	IMP	UniProt	cell division	1 2 3 4 5 6
GO:0010200	RCA	Gene Ontology	response to chitin	1
GO:0006464	IEA	UniProt	cellular protein modification process	1 2 3 4 5
GO:0015031	IEA	UniProt	protein transport	1 2 3 4 5
GO:0036211	IEA	PLAZA Homology	protein modification process	HOM03M002747

GO term	Evidence(s)	Provider	Description	Source
GO:0043130	IDA	UniProt	ubiquitin binding	1 2 3 4 5 6
GO:0005515	IPI	Gene Ontology	protein binding	1

GO term	Evidence(s)	Provider	Description	Source
GO:0005634	ISM	Gene Ontology	nucleus	1
GO:0000813	ISS	UniProt	ESCRT I complex	1 2 3 4 5 6
GO:0005769	IDA	UniProt	early endosome	1 2 3 4 5 6
GO:0005770	IDA	UniProt	late endosome	1 2 3 4 5 6
GO:0043234	IDA	Gene Ontology	protein complex	1

Experimental Evidence

Electronic Evidence

Computational Reviewed Evidence

InterPro	Description
IPR016135	Ubiquitin-conjugating enzyme/RWD-like
IPR017916	Steadiness box
IPR008883	Ubiquitin E2 variant, N-terminal

Mapman id	Description
35.2	not assigned.unknown

No SignalP domains detected for this gene.