Gene: AT3G08040 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G08040
Transcript Identifier
AT3G08040.1
Gene Type
Coding gene
Location
3 : 2566593-2569397 : negative

Family

Gene family
HOM03M000704
(98 genes in 16 species)
specific family
Subfamily
ORTHO03M014134
(3 genes in 3 species)
specific family

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Descriptions

Description
MATE efflux family protein
Curated Summary
Encodes a member of the MATE (multidrug and toxin efflux family), expressed in roots but not shoots. Mutants accumulate excess iron, manganese and zinc, and express root Fe(III) chelatase activity even under iron sufficiency conditions. FRD3 is likely to function in root xylem loading of an iron chelator or other factor necessary for efficient iron uptake out of the xylem or apoplastic space and into leaf cells.
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Identifiers

Identifier Name
aliasMANGANESE ACCUMULATOR 1
aliasATFRD3
aliasMAN1
aliasFRD3
aliasFERRIC REDUCTASE DEFECTIVE 3
uniprotQ9SFB0

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006879IMPUniProtcellular iron ion homeostasis1 2 3 4 5 6 7 8
GO:0071281IEPUniProtcellular response to iron ion1 2 3 4 5 6 7 8
GO:0071369IEPUniProtcellular response to ethylene stimulus1 2 3 4 5 6 7 8
GO:0071732IEPUniProtcellular response to nitric oxide1 2 3 4 5 6 7 8
GO:0006826RCAGene Ontologyiron ion transport1
GO:0010106RCAGene Ontologycellular response to iron ion starvation1
GO:0010167RCAGene Ontologyresponse to nitrate1
GO:0010413RCAGene Ontologyglucuronoxylan metabolic process1
GO:0015706RCAGene Ontologynitrate transport1
GO:0045492RCAGene Ontologyxylan biosynthetic process1
GO:0006855IEAInterProdrug transmembrane transport
GO:0055085IEAInterProtransmembrane transport

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0015297IEA, ISSUniProtantiporter activity1 2 3 4 5 6 7 8
GO:0005215ISSGene Ontologytransporter activity1
GO:0015137IDAUniProtcitrate transmembrane transporter activity1 2 3 4 5 6 7 8
GO:0015238IEAUniProtdrug transmembrane transporter activity1 2 3 4 5 6 7

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886IDA, ISM, UniProtplasma membrane1 2 3 4 5 6 7 8 9
GO:0016020ISS, IEAGene Ontologymembrane1
GO:0016021IEAUniProtintegral to membrane1 2 3 4 5 6 7

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002528Multi antimicrobial extrusion protein

Mapman id Description
15.1metal handling.acquisition
No SignalP domains detected for this gene.