Gene: AT3G06860 (Arabidopsis thaliana)

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Gene Identifier
AT3G06860
Transcript Identifier
AT3G06860.1
Gene Type
Coding gene
Location
3 : 2161926-2166009 : positive

Family

Gene family
HOM03M000943
(75 genes in 16 species)
specific family

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Descriptions

Description
multifunctional protein 2
Curated Summary
Encodes a multifunctional protein. Involved in peroxisomal fatty acid beta oxidation. Loss-of-function mutant lacks hydroxyacyl-CoA dehydrogenase activity and have reduced levels of long-chain enoyl-CoA hydratase activity. The mutant has fewer but larger peroxisomes.
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Identifiers

Identifier Name
aliasMULTIFUNCTIONAL PROTEIN 2
aliasmultifunctional protein 2
aliasATMFP2
aliasMFP2
uniprotQ9ZPI5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006635IEP, RCA, UniProtfatty acid beta-oxidation1 2 3 4 5 6 7 8
GO:0007031RCAGene Ontologyperoxisome organization1
GO:0009062RCAGene Ontologyfatty acid catabolic process1
GO:0009407RCAGene Ontologytoxin catabolic process1
GO:0043161RCAGene Ontologyproteasome-mediated ubiquitin-dependent protein catabolic process1
GO:0051788RCAGene Ontologyresponse to misfolded protein1
GO:0080129RCAGene Ontologyproteasome core complex assembly1
GO:0008152IEAInterPrometabolic process
GO:0006631IEAInterProfatty acid metabolic process
GO:0055114IEAInterProoxidation-reduction process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004300IEA, IMPUniProtenoyl-CoA hydratase activity1 2 3 4 5 6 7
GO:0003857IDA, IMPIEA, UniProt3-hydroxyacyl-CoA dehydrogenase activity1 2 3 4 5 6 7 8
GO:0016508IDAUniProtlong-chain-enoyl-CoA hydratase activity1 2 3 4 5 6 7
GO:0008692IEAUniProt3-hydroxybutyryl-CoA epimerase activity1 2 3 4 5 6
GO:0050662IEAUniProtcoenzyme binding1 2 3 4 5 6
GO:0004165IEAUniProtdodecenoyl-CoA delta-isomerase activity1 2 3 4 5 6
GO:0016491IEAInterProoxidoreductase activity
GO:0003824IEAInterProcatalytic activity
GO:0016616IEAInterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1
GO:0005777IDA, TAS, UniProtperoxisome1 2 3 4 5 6 7 8
GO:0005730IDAUniProtnucleolus1 2 3 4 5 6 7
GO:0005618IDAUniProtcell wall1 2 3 4 5 6 7
GO:0005829RCAGene Ontologycytosol1
GO:0009506IDAUniProtplasmodesma1 2 3 4 5 6 7
GO:0009514IEAUniProtglyoxysome1 2 3 4 5 6

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR016040NAD(P)-binding domain
IPR0061803-hydroxyacyl-CoA dehydrogenase, conserved site
IPR0089276-phosphogluconate dehydrogenase, C-terminal-like
IPR0061083-hydroxyacyl-CoA dehydrogenase, C-terminal
IPR0061763-hydroxyacyl-CoA dehydrogenase, NAD binding
IPR013328Dehydrogenase, multihelical
IPR001753Crotonase superfamily
IPR018376Enoyl-CoA hydratase/isomerase, conserved site

Mapman id Description
11.9.4.9lipid metabolism.lipid degradation.beta-oxidation.multifunctional
No SignalP domains detected for this gene.