Gene: AT3G06483 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G06483
Transcript Identifier
AT3G06483.1
Gene Type
Coding gene
Location
3 : 1990727-1992581 : negative

Family

Gene family
HOM03M002737
(32 genes in 16 species)
specific family

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Descriptions

Description
pyruvate dehydrogenase kinase
Curated Summary
Pyruvate dehydrogenase kinase (PDK) specifically phosphorylates the E1α subunit of the pyruvate dehydrogenase complex (PDC) on a Ser residue using ATP as a phosphate donor. PDK is a unique type of protein kinase having a His-kinase-like sequence but Ser-kinase activity. Site-directed mutagenesis and structural analysis indicate that PDK belongs to the GHKL superfamily.
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Identifiers

Identifier Name
aliaspyruvate dehydrogenase kinase
aliasPDK
aliasATPDHK
uniprotQ9SBJ1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0046777IDAUniProtprotein autophosphorylation1 2 3 4 5 6 7 8 9
GO:0030003RCAGene Ontologycellular cation homeostasis1
GO:0070838RCAGene Ontologydivalent metal ion transport1
GO:0016310IEAInterProphosphorylation

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005524IDA, ISSIEA, UniProtATP binding1 2 3 4 5 6 7 8 9 10
GO:0004740IEA, IMPUniProtpyruvate dehydrogenase (acetyl-transferring) kinase activity1 2 3 4 5 6 7 8 9
GO:0009927IDAUniProthistidine phosphotransfer kinase activity1 2 3 4 5 6 7 8 9
GO:0042803IPIGene Ontologyprotein homodimerization activity1
GO:0004674IEAUniProtprotein serine/threonine kinase activity1 2 3 4 5 6 7 8
GO:0016772IEAInterProtransferase activity, transferring phosphorus-containing groups

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005739NAS, ISMUniProtmitochondrion1 2 3 4 5 6 7 8 9 10

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004358Signal transduction histidine kinase-related protein, C-terminal
IPR005467Signal transduction histidine kinase, core
IPR018955Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal
IPR003594Histidine kinase-like ATPase, ATP-binding domain

Mapman id Description
30.1.2signalling.in sugar and nutrient physiology.pyruvate dehydrogenase kinase
No SignalP domains detected for this gene.