Gene: AT3G03300 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT3G03300
Transcript Identifier
AT3G03300.1
Gene Type
Coding gene
Location
3 : 768020-774833 : negative

Family

Gene family
HOM03M000334
(174 genes in 15 species)
specific family
Subfamily
ORTHO03M002980
(8 genes in 8 species)
specific family

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Descriptions

Description
dicer-like 2
Curated Summary
Encodes a Dicer-like protein that functions in the antiviral silencing response in turnip-crinkle virus-infected plants but not in TMV or CMV-strain-Y-infected plants. Involved in the production of ta-siRNAs. Partially antagonizes the production of miRNAs by DCL1. Substitutes for DCL4 to produce viral siRNA when DCL4 is missing or inhibited. Able to produce siRNAs but not miRNAs.
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Identifiers

Identifier Name
aliasdicer-like 2
aliasDICER-LIKE 2
aliasDCL2
aliasATDCL2
uniprotQ3EBC8

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0010216IMPUniProtmaintenance of DNA methylation1 2 3 4 5 6 7 8 9 10
GO:0010267IMP, RCA, UniProtproduction of ta-siRNAs involved in RNA interference1 2 3 4 5 6 7 8 9 10 11
GO:0051607IMP, RCA, UniProtdefense response to virus1 2 3 4 5 6 7 8 9 10 11
GO:0035196IGI, RCAGene Ontologyproduction of miRNAs involved in gene silencing by miRNA1 2
GO:0000398RCAGene OntologymRNA splicing, via spliceosome1
GO:0006306RCAGene OntologyDNA methylation1
GO:0006342RCAGene Ontologychromatin silencing1
GO:0006355RCAGene Ontologyregulation of transcription, DNA-dependent1
GO:0007267RCAGene Ontologycell-cell signaling1
GO:0009616RCAGene Ontologyvirus induced gene silencing1
GO:0009855RCAGene Ontologydetermination of bilateral symmetry1
GO:0010014RCAGene Ontologymeristem initiation1
GO:0010050RCAGene Ontologyvegetative phase change1
GO:0010073RCAGene Ontologymeristem maintenance1
GO:0016569RCAGene Ontologycovalent chromatin modification1
GO:0030422RCAGene Ontologyproduction of siRNA involved in RNA interference1
GO:0031047RCAGene Ontologygene silencing by RNA1
GO:0043687RCAGene Ontologypost-translational protein modification1
GO:0045893RCAGene Ontologypositive regulation of transcription, DNA-dependent1
GO:0090305IEAUniProtnucleic acid phosphodiester bond hydrolysis1 2 3 4 5 6 7 8 9
GO:0006396IEAInterProRNA processing

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004525IEA, ISSUniProtribonuclease III activity1 2 3 4 5 6 7 8 9 10
GO:0008026IEA, ISSUniProtATP-dependent helicase activity1 2 3 4 5 6 7 8 9 10
GO:0005515IPI, IEAGene Ontologyprotein binding1
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8 9
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5 6 7 8 9
GO:0003723IEAUniProtRNA binding1 2 3 4 5 6 7 8 9
GO:0016891IEAInterProendoribonuclease activity, producing 5'-phosphomonoesters
GO:0004386IEAInterProhelicase activity
GO:0003676IEAInterPronucleic acid binding
GO:0016893IEAPLAZA Homologyendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersHOM03M000334
GO:0004521IEAPLAZA Homologyendoribonuclease activityHOM03M000334

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IEA, ISMUniProtnucleus1 2 3 4 5 6 7 8 9 10
GO:0005737IEAUniProtcytoplasm1 2 3 4 5 6 7 8 9

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR014720Double-stranded RNA-binding domain
IPR000999Ribonuclease III domain
IPR014001Helicase, superfamily 1/2, ATP-binding domain
IPR001650Helicase, C-terminal
IPR005034Dicer dimerisation domain
IPR003100Argonaute/Dicer protein, PAZ domain
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR011545DNA/RNA helicase, DEAD/DEAH box type, N-terminal

Mapman id Description
27.1.20RNA.processing.degradation dicer
No SignalP domains detected for this gene.