Gene: AT2G47000 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT2G47000
Transcript Identifier
AT2G47000.1
Gene Type
Coding gene
Location
2 : 19310008-19314750 : negative

Family

Gene family
HOM03M000080
(564 genes in 16 species)
specific family
Subfamily
ORTHO03M013091
(3 genes in 3 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
ATP binding cassette subfamily B4
Curated Summary
Encodes an auxin efflux transmembrane transporter that is a member of the multidrug resistance P-glycoprotein (MDR/PGP) subfamily of ABC transporters. Functions in the basipetal redirection of auxin from the root tip. Exhibits apolar plasma membrane localization in the root cap and polar localization in tissues above and is involved in root hair elongation.
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Identifiers

Identifier Name
aliasP-GLYCOPROTEIN 4
aliasATPGP4
aliasAtABCB4
aliasPGP4
aliasABCB4
aliasMULTIDRUG RESISTANCE 4
aliasMDR4
aliasATP-binding cassette B4
aliasARABIDOPSIS P-GLYCOPROTEIN 4
uniprotO80725

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009733IEP, RCAGene Ontologyresponse to auxin1 2
GO:0009735IEP, RCA, UniProtresponse to cytokinin1 2 3 4 5 6 7 8 9 10
GO:0009926TASGene Ontologyauxin polar transport1
GO:0009630IMPUniProtgravitropism1 2 3 4 5 6 7 8 9
GO:0010540IMPUniProtbasipetal auxin transport1 2 3 4 5 6 7 8 9
GO:0010315IDA, IMPGene Ontologyauxin efflux1 2
GO:0048767IMP, RCA, UniProtroot hair elongation1 2 3 4 5 6 7 8 9 10
GO:0000303RCAGene Ontologyresponse to superoxide1
GO:0006888RCAGene OntologyER to Golgi vesicle-mediated transport1
GO:0007165RCAGene Ontologysignal transduction1
GO:0009407RCAGene Ontologytoxin catabolic process1
GO:0009414RCAGene Ontologyresponse to water deprivation1
GO:0009651RCAGene Ontologyresponse to salt stress1
GO:0009723RCAGene Ontologyresponse to ethylene1
GO:0009737RCAGene Ontologyresponse to abscisic acid1
GO:0009738RCAGene Ontologyabscisic acid-activated signaling pathway1
GO:0009743RCAGene Ontologyresponse to carbohydrate1
GO:0009753RCAGene Ontologyresponse to jasmonic acid1
GO:0009873RCAGene Ontologyethylene mediated signaling pathway1
GO:0010583RCAGene Ontologyresponse to cyclopentenone1
GO:0042538RCAGene Ontologyhyperosmotic salinity response1
GO:0043090RCAGene Ontologyamino acid import1
GO:0043161RCAGene Ontologyproteasome-mediated ubiquitin-dependent protein catabolic process1
GO:0043248RCAGene Ontologyproteasome assembly1
GO:0051788RCAGene Ontologyresponse to misfolded protein1
GO:0060919IDAGene Ontologyauxin influx1
GO:0006810IEAInterProtransport
GO:0055085IEAInterProtransmembrane transport
GO:0044765IEAPLAZA Homologysingle-organism transportHOM03M000080
GO:0051234IEAPLAZA Homologyestablishment of localizationHOM03M000080
GO:0051179IEAPLAZA HomologylocalizationHOM03M000080

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0042626ISS, IEAGene OntologyATPase activity, coupled to transmembrane movement of substances1
GO:0008559IDAUniProtxenobiotic-transporting ATPase activity1 2 3 4 5 6 7 8 9
GO:0010328IDAUniProtauxin influx transmembrane transporter activity1 2 3 4 5 6 7 8 9
GO:0010329IDAUniProtauxin efflux transmembrane transporter activity1 2 3 4 5 6 7 8 9
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8
GO:0017111IEAInterPronucleoside-triphosphatase activity
GO:0000166IEAInterPronucleotide binding
GO:0016887IEAInterProATPase activity
GO:0005215IEAPLAZA Homologytransporter activityHOM03M000080
GO:0032555IEAPLAZA Homologypurine ribonucleotide bindingHOM03M000080
GO:0016817IEAPLAZA Homologyhydrolase activity, acting on acid anhydridesHOM03M000080
GO:0043168IEAPLAZA Homologyanion bindingHOM03M000080
GO:0032553IEAPLAZA Homologyribonucleotide bindingHOM03M000080
GO:0042623IEAPLAZA HomologyATPase activity, coupledHOM03M000080
GO:0043167IEAPLAZA Homologyion bindingHOM03M000080
GO:0035639IEAPLAZA Homologypurine ribonucleoside triphosphate bindingHOM03M000080
GO:0097367IEAPLAZA Homologycarbohydrate derivative bindingHOM03M000080
GO:0022804IEAPLAZA Homologyactive transmembrane transporter activityHOM03M000080
GO:0016818IEAPLAZA Homologyhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesHOM03M000080
GO:0032559IEAPLAZA Homologyadenyl ribonucleotide bindingHOM03M000080
GO:1901265IEAPLAZA Homologynucleoside phosphate bindingHOM03M000080
GO:0016462IEAPLAZA Homologypyrophosphatase activityHOM03M000080
GO:0001882IEAPLAZA Homologynucleoside bindingHOM03M000080
GO:0030554IEAPLAZA Homologyadenyl nucleotide bindingHOM03M000080
GO:0016820IEAPLAZA Homologyhydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesHOM03M000080
GO:0017076IEAPLAZA Homologypurine nucleotide bindingHOM03M000080
GO:0097159IEAPLAZA Homologyorganic cyclic compound bindingHOM03M000080
GO:0015399IEAPLAZA Homologyprimary active transmembrane transporter activityHOM03M000080
GO:0015405IEAPLAZA HomologyP-P-bond-hydrolysis-driven transmembrane transporter activityHOM03M000080
GO:0022857IEAPLAZA Homologytransmembrane transporter activityHOM03M000080
GO:0036094IEAPLAZA Homologysmall molecule bindingHOM03M000080
GO:0032549IEAPLAZA Homologyribonucleoside bindingHOM03M000080
GO:0016787IEAPLAZA Homologyhydrolase activityHOM03M000080
GO:1901363IEAPLAZA Homologyheterocyclic compound bindingHOM03M000080
GO:0001883IEAPLAZA Homologypurine nucleoside bindingHOM03M000080
GO:0032550IEAPLAZA Homologypurine ribonucleoside bindingHOM03M000080
GO:0043492IEAPLAZA HomologyATPase activity, coupled to movement of substancesHOM03M000080

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1
GO:0005886IDAUniProtplasma membrane1 2 3 4 5 6 7 8 9
GO:0016020IDAGene Ontologymembrane1
GO:0009506IDAUniProtplasmodesma1 2 3 4 5 6 7 8 9
GO:0016021IEAUniProtintegral to membrane1 2 3 4 5 6 7 8
GO:0031224IEAPLAZA Homologyintrinsic to membraneHOM03M000080
GO:0044425IEAPLAZA Homologymembrane partHOM03M000080

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011527ABC transporter type 1, transmembrane domain
IPR003439ABC transporter-like
IPR001140ABC transporter, transmembrane domain
IPR003593AAA+ ATPase domain
IPR027417P-loop containing nucleoside triphosphate hydrolase
IPR017871ABC transporter, conserved site

Mapman id Description
34.16transport.ABC transporters and multidrug resistance systems
No SignalP domains detected for this gene.