Gene: AT2G34650 (Arabidopsis thaliana)

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Gene Identifier
AT2G34650
Transcript Identifier
AT2G34650.1
Gene Type
Coding gene
Location
2 : 14589934-14591557 : negative

Family

Gene family
HOM03M000079
(579 genes in 16 species)
specific family
Subfamily
ORTHO03M011340
(4 genes in 4 species)
specific family

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Descriptions

Description
Protein kinase superfamily protein
Curated Summary
Encodes a protein serine/threonine kinase that may act as a positive regulator of cellular auxin efflux, as a a binary switch for PIN polarity, and as a negative regulator of auxin signaling. Recessive mutants exhibit similar phenotypes as pin-formed mutants in flowers and inflorescence but distinct phenotypes in cotyledons and leaves. Expressed in the vascular tissue proximal to root and shoot meristems, shoot apex, and embryos. Expression is induced by auxin. Overexpression of the gene results in phenotypes in the root and shoot similar to those found in auxin-insensitive mutants. The protein physically interacts with TCH3 (TOUCH3) and PID-BINDING PROTEIN 1 (PBP1), a previously uncharacterized protein containing putative EF-hand calcium-binding motifs. Acts together with ENP (ENHANCER OF PINOID) to instruct precursor cells to elaborate cotyledons in the transition stage embryo. Interacts with PDK1. PID autophosphorylation is required for the ability of PID to phosphorylate an exogenous substrate. PID activation loop is required for PDK1-dependent PID phosphorylation and requires the PIF domain. Negative regulator of root hair growth. PID kinase activity is critical for the inhibition of root hair growth and for maintaining the proper subcellular localization of PID.
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Identifiers

Identifier Name
aliasABR
aliasABRUPTUS
aliasPID
aliasPINOID
uniprotO64682

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009734IMPUniProtauxin mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0009926IMP, RCA, UniProtauxin polar transport1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0009733IEP, RCAGene Ontologyresponse to auxin1 2
GO:0048825IGIUniProtcotyledon development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0048766IMPUniProtroot hair initiation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0048767IMPUniProtroot hair elongation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0048827IGIGene Ontologyphyllome development1
GO:0009958IMPUniProtpositive gravitropism1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0080167IEPUniProtresponse to karrikin1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0008361RCAGene Ontologyregulation of cell size1
GO:0009637RCAGene Ontologyresponse to blue light1
GO:0009640RCAGene Ontologyphotomorphogenesis1
GO:0043481RCAGene Ontologyanthocyanin accumulation in tissues in response to UV light1
GO:0048364RCAGene Ontologyroot development1
GO:0048443RCAGene Ontologystamen development1
GO:0006468IEAInterProprotein phosphorylation
GO:0009908ISOPLAZA Integrative Orthologyflower developmentOS12G42020
GO:0044260IEAPLAZA Homologycellular macromolecule metabolic processHOM03M000079
GO:0006796IEAPLAZA Homologyphosphate-containing compound metabolic processHOM03M000079
GO:0006793IEAPLAZA Homologyphosphorus metabolic processHOM03M000079
GO:0043170IEAPLAZA Homologymacromolecule metabolic processHOM03M000079
GO:0044237IEAPLAZA Homologycellular metabolic processHOM03M000079
GO:0044238IEAPLAZA Homologyprimary metabolic processHOM03M000079
GO:0016310IEAPLAZA HomologyphosphorylationHOM03M000079
GO:0043412IEAPLAZA Homologymacromolecule modificationHOM03M000079
GO:0071704IEAPLAZA Homologyorganic substance metabolic processHOM03M000079
GO:0044267IEAPLAZA Homologycellular protein metabolic processHOM03M000079
GO:0019538IEAPLAZA Homologyprotein metabolic processHOM03M000079
GO:0036211IEAPLAZA Homologyprotein modification processHOM03M000079
GO:0006464IEAPLAZA Homologycellular protein modification processHOM03M000079

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016301ISSGene Ontologykinase activity1
GO:0004674IDA, ISSIEA, UniProtprotein serine/threonine kinase activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
GO:0005515IPIGene Ontologyprotein binding1
GO:0004672IDA, IEAGene Ontologyprotein kinase activity1
GO:0042802IPIGene Ontologyidentical protein binding1
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
GO:0016772IEAInterProtransferase activity, transferring phosphorus-containing groups
GO:0032555IEAPLAZA Homologypurine ribonucleotide bindingHOM03M000079
GO:0043168IEAPLAZA Homologyanion bindingHOM03M000079
GO:0032553IEAPLAZA Homologyribonucleotide bindingHOM03M000079
GO:0043167IEAPLAZA Homologyion bindingHOM03M000079
GO:0035639IEAPLAZA Homologypurine ribonucleoside triphosphate bindingHOM03M000079
GO:0097367IEAPLAZA Homologycarbohydrate derivative bindingHOM03M000079
GO:0032559IEAPLAZA Homologyadenyl ribonucleotide bindingHOM03M000079
GO:1901265IEAPLAZA Homologynucleoside phosphate bindingHOM03M000079
GO:0000166IEAPLAZA Homologynucleotide bindingHOM03M000079
GO:0001882IEAPLAZA Homologynucleoside bindingHOM03M000079
GO:0030554IEAPLAZA Homologyadenyl nucleotide bindingHOM03M000079
GO:0016773IEAPLAZA Homologyphosphotransferase activity, alcohol group as acceptorHOM03M000079
GO:0017076IEAPLAZA Homologypurine nucleotide bindingHOM03M000079
GO:0097159IEAPLAZA Homologyorganic cyclic compound bindingHOM03M000079
GO:0036094IEAPLAZA Homologysmall molecule bindingHOM03M000079
GO:0032549IEAPLAZA Homologyribonucleoside bindingHOM03M000079
GO:1901363IEAPLAZA Homologyheterocyclic compound bindingHOM03M000079
GO:0001883IEAPLAZA Homologypurine nucleoside bindingHOM03M000079
GO:0032550IEAPLAZA Homologypurine ribonucleoside bindingHOM03M000079
GO:0016740IEAPLAZA Homologytransferase activityHOM03M000079

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1
GO:0009986IDAUniProtcell surface1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
GO:0005829IEAUniProtcytosol1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine- / dual specificity protein kinase, catalytic domain
IPR011009Protein kinase-like domain
IPR008271Serine/threonine-protein kinase, active site

Mapman id Description
29.4protein.postranslational modification
No SignalP domains detected for this gene.