Gene: AT2G30110 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT2G30110
Transcript Identifier
AT2G30110.1
Gene Type
Coding gene
Location
2 : 12852632-12857369 : negative

Family

Gene family
HOM03M001356
(55 genes in 16 species)
specific family
Subfamily
ORTHO03M000297
(17 genes in 13 species)
specific family

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Descriptions

Description
ubiquitin-activating enzyme 1
Curated Summary
Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling.
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Identifiers

Identifier Name
aliasMODIFIER OF SNC1 5
aliasUBA1
aliasubiquitin-activating enzyme 1
aliasMOS5
aliasATUBA1
uniprotP93028

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006511TASGene Ontologyubiquitin-dependent protein catabolic process1
GO:0046686IEPUniProtresponse to cadmium ion1 2 3 4 5
GO:0051707IMPUniProtresponse to other organism1 2 3 4 5
GO:0006486RCAGene Ontologyprotein glycosylation1
GO:0006487RCAGene Ontologyprotein N-linked glycosylation1
GO:0006635RCAGene Ontologyfatty acid beta-oxidation1
GO:0006888RCAGene OntologyER to Golgi vesicle-mediated transport1
GO:0009407RCAGene Ontologytoxin catabolic process1
GO:0043090RCAGene Ontologyamino acid import1
GO:0043161RCAGene Ontologyproteasome-mediated ubiquitin-dependent protein catabolic process1
GO:0051788RCAGene Ontologyresponse to misfolded protein1
GO:0080129RCAGene Ontologyproteasome core complex assembly1
GO:0016567IDAGene Ontologyprotein ubiquitination1
GO:0006464IEAInterProcellular protein modification process
GO:0036211IEAPLAZA Homologyprotein modification processHOM03M001356

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004839IMP, ISSGene Ontologyubiquitin activating enzyme activity1 2
GO:0004842IDAUniProtubiquitin-protein ligase activity1 2 3 4 5
GO:0005524IEAUniProtATP binding1 2 3 4
GO:0008641IEAUniProtsmall protein activating enzyme activity1 2 3 4
GO:0003824IEAInterProcatalytic activity

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1
GO:0005886IDAUniProtplasma membrane1 2 3 4 5
GO:0005829IDAUniProtcytosol1 2 3 4 5
GO:0009506IDAUniProtplasmodesma1 2 3 4 5

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR016040NAD(P)-binding domain
IPR000594UBA/THIF-type NAD/FAD binding fold
IPR000127Ubiquitin-activating enzyme repeat
IPR018075Ubiquitin-activating enzyme, E1
IPR019572Ubiquitin-activating enzyme
IPR000011Ubiquitin/SUMO-activating enzyme E1
IPR018965Ubiquitin-activating enzyme e1, C-terminal
IPR009036Molybdenum cofactor biosynthesis, MoeB
IPR023280Ubiquitin-like 1 activating enzyme, catalytic cysteine domain
IPR018074Ubiquitin-activating enzyme, E1, active site

Mapman id Description
29.5.11.2protein.degradation.ubiquitin.E1
No SignalP domains detected for this gene.