Gene: AT2G22780 (Arabidopsis thaliana)

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Gene Identifier
AT2G22780
Transcript Identifier
AT2G22780.1
Gene Type
Coding gene
Location
2 : 9689995-9691923 : negative

Family

Gene family
HOM03M000690
(100 genes in 16 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
peroxisomal NAD-malate dehydrogenase 1
Curated Summary
encodes an peroxisomal NAD-malate dehydrogenase that is involved in fatty acid beta-oxidation through providing NAD to the process of converting fatty acyl CoA to acetyl CoA.
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Identifiers

Identifier Name
aliasperoxisomal NAD-malate dehydrogenase 1
aliasPMDH1
uniprotO82399

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0031998IMP, IGIUniProtregulation of fatty acid beta-oxidation1 2 3 4
GO:0080093IMPUniProtregulation of photorespiration1 2 3
GO:0006635RCAGene Ontologyfatty acid beta-oxidation1
GO:0007031RCAGene Ontologyperoxisome organization1
GO:0009062RCAGene Ontologyfatty acid catabolic process1
GO:0006097IEAUniProtglyoxylate cycle1 2
GO:0006108IEAUniProtmalate metabolic process1 2
GO:0006099IEAUniProttricarboxylic acid cycle1 2
GO:0044262IEAInterProcellular carbohydrate metabolic process
GO:0005975IEAInterProcarbohydrate metabolic process
GO:0055114IEAInterProoxidation-reduction process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016615ISS, IEAGene Ontologymalate dehydrogenase activity1
GO:0030060IEAUniProtL-malate dehydrogenase activity1 2
GO:0016491IEAInterProoxidoreductase activity
GO:0003824IEAInterProcatalytic activity
GO:0016616IEAInterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737ISMGene Ontologycytoplasm1
GO:0005777IDAUniProtperoxisome1 2 3
GO:0009507IDAUniProtchloroplast1 2 3
GO:0009514IEAUniProtglyoxysome1 2

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR010097Malate dehydrogenase, type 1
IPR015955Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
IPR016040NAD(P)-binding domain
IPR001236Lactate/malate dehydrogenase, N-terminal
IPR001252Malate dehydrogenase, active site
IPR001557L-lactate/malate dehydrogenase
IPR022383Lactate/malate dehydrogenase, C-terminal

Mapman id Description
6.3gluconeogenesis / glyoxylate cycle.Malate DH
No SignalP domains detected for this gene.