Gene: AT2G20000 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
2 : 8632324-8636900 : negative


Gene family
(26 genes in 16 species)
specific family

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CDC27 family protein
Curated Summary
Required for cell division and cell differentiation in meristems. Encodes a homolog of the CDC27 subunit of the anaphase-promoting complex (APC). Unlike other CDC27 homologs in Arabidopsis, its transcription is cell cycle regulated. Strong hbt mutants give rise to seedlings that lack an anatomically recognizable quiescent center and differentiated columella root cap cells, the cell types derived from the wild-type hypophysis. Furthermore, they have no mitotically active root meristem and lack a differentiated lateral root cap.
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Identifier Name





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007346IMP, RCATAS, UniProtregulation of mitotic cell cycle1 2 3 4 5 6 7
GO:0009733IMPUniProtresponse to auxin1 2 3 4 5
GO:0030154IMP, IEA, UniProtcell differentiation1 2 3 4 5
GO:0007276IGI, RCA, UniProtgamete generation1 2 3 4 5 6
GO:0051302IGI, RCAIEA, UniProtregulation of cell division1 2 3 4 5 6
GO:0051510IGI, RCA, UniProtregulation of unidimensional cell growth1 2 3 4 5 6
GO:0006312RCAGene Ontologymitotic recombination1
GO:0009560RCAGene Ontologyembryo sac egg cell differentiation1
GO:0009965RCAGene Ontologyleaf morphogenesis1
GO:0010048RCAGene Ontologyvernalization response1
GO:0032875RCAGene Ontologyregulation of DNA endoreduplication1
GO:0042023RCAGene OntologyDNA endoreduplication1
GO:0043161RCAGene Ontologyproteasome-mediated ubiquitin-dependent protein catabolic process1
GO:0043248RCAGene Ontologyproteasome assembly1
GO:0051788RCAGene Ontologyresponse to misfolded protein1
GO:0010071IMPUniProtroot meristem specification1 2 3 4 5
GO:0048364IMPGene Ontologyroot development1
GO:0048829IMPUniProtroot cap development1 2 3 4 5
GO:0051301IEAUniProtcell division1 2 3 4
GO:0007067IEAUniProtmitosis1 2 3 4
GO:0016567IEAUniProtprotein ubiquitination1 2 3 4

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0005515IPI, IEAGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISMGene Ontologynucleus1 2
GO:0005680IPI, ISS, TASIEA, UniProtanaphase-promoting complex1 2 3 4 5 6 7
GO:0005819IDAUniProtspindle1 2 3 4 5
GO:0009504IDAUniProtcell plate1 2 3 4 5

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR019734Tetratricopeptide repeat
IPR001440Tetratricopeptide TPR1
IPR013026Tetratricopeptide repeat-containing domain
IPR013105Tetratricopeptide TPR2
IPR026819Cell division cycle protein 27A/B, plant
IPR011990Tetratricopeptide-like helical

Mapman id Description
No SignalP domains detected for this gene.