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WorkbenchGene: AT2G17950 (Arabidopsis thaliana)
Overview 
- Gene Identifier
- AT2G17950
- Transcript Identifier
- AT2G17950.1
- Gene Type
- Coding gene
- Location
- 2 : 7809100-7810671 : negative
Family
- Gene family
Descriptions
- Description
-
Homeodomain-like superfamily protein
- Curated Summary
-
Homeobox gene controlling the stem cell pool. Expressed in the stem cell organizing center of meristems. Required to keep the stem cells in an undifferentiated state. Regulation of WUS transcription is a central checkpoint in stem cell control. The size of the WUS expression domain controls the size of the stem cell population through WUS indirectly activating the expression of CLAVATA3 (CLV3) in the stem cells and CLV3 repressing WUS transcription through the CLV1 receptor kinase signaling pathway. Repression of WUS transcription through AGAMOUS (AG) activity controls stem cell activity in the determinate floral meristem. Binds to TAAT element core motif. WUS is also involved in cell differentiation during anther development.
Identifiers
| Identifier | Name |
|---|---|
| alias | WUS |
| alias | WUS1 |
| alias | WUSCHEL |
| alias | WUSCHEL 1 |
| alias | PGA6 |
| uniprot | Q9SB92 |
Toolbox
Explore
- ...the colinearity of this gene with other genomes.
- ...the local gene organization for homologous genes.
- ...the phylogenetic tree of the homologous gene family.
- ...the orthologs using the Integrative Orthology Viewer.
- ...the conserved binding sites (upstream/downstream,intron)
View
Biological Process
| GO term | Evidence(s) | Provider | Description | Source |
|---|---|---|---|---|
| GO:0006355 | TAS, IEA | Gene Ontology | regulation of transcription, DNA-dependent | 1 |
| GO:0048653 | IMP | Gene Ontology | anther development | 1 |
| GO:0080166 | IMP | UniProt | stomium development | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 |
| GO:0010492 | IGI | UniProt | maintenance of shoot apical meristem identity | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 |
| GO:0009827 | RCA | Gene Ontology | plant-type cell wall modification | 1 |
| GO:0009860 | RCA | Gene Ontology | pollen tube growth | 1 |
| GO:0010093 | RCA | Gene Ontology | specification of floral organ identity | 1 |
| GO:0048440 | RCA | Gene Ontology | carpel development | 1 |
| GO:0019827 | IMP | Gene Ontology | stem cell maintenance | 1 |
| GO:0048477 | IEA | UniProt | oogenesis | 1 2 3 4 5 6 7 8 9 10 11 12 13 |
| GO:0006351 | IEA | UniProt | transcription, DNA-templated | 1 2 3 4 5 6 7 8 9 10 11 12 13 |
| GO:2001141 | IEA | PLAZA Homology | regulation of RNA biosynthetic process | HOM03M000493 |
Molecular Function
| GO term | Evidence(s) | Provider | Description | Source |
|---|---|---|---|---|
| GO:0003677 | ISS, IEA | Gene Ontology | DNA binding | 1 |
| GO:0003700 | ISS, TASIEA, | UniProt | sequence-specific DNA binding transcription factor activity | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 |
| GO:0005515 | IPI | Gene Ontology | protein binding | 1 |
| GO:0043565 | IEA | UniProt | sequence-specific DNA binding | 1 2 3 4 5 6 7 8 9 10 11 12 13 |
Cellular Component
| GO term | Evidence(s) | Provider | Description | Source |
|---|---|---|---|---|
| GO:0005634 | IEA, ISM | UniProt | nucleus | 1 2 3 4 5 6 7 8 9 10 11 12 13 14 |
Color Legend
| Experimental Evidence |
| Electronic Evidence |
| Computational Reviewed Evidence |
| Mapman id | Description |
|---|---|
| 27.3.22 | RNA.regulation of transcription.HB,Homeobox transcription factor family |
No SignalP domains detected for this gene.