Gene: AT2G17950 (Arabidopsis thaliana)

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Gene Identifier
AT2G17950
Transcript Identifier
AT2G17950.1
Gene Type
Coding gene
Location
2 : 7809100-7810671 : negative

Family

Gene family
HOM03M000493
(128 genes in 15 species)
specific family

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Descriptions

Description
Homeodomain-like superfamily protein
Curated Summary
Homeobox gene controlling the stem cell pool. Expressed in the stem cell organizing center of meristems. Required to keep the stem cells in an undifferentiated state. Regulation of WUS transcription is a central checkpoint in stem cell control. The size of the WUS expression domain controls the size of the stem cell population through WUS indirectly activating the expression of CLAVATA3 (CLV3) in the stem cells and CLV3 repressing WUS transcription through the CLV1 receptor kinase signaling pathway. Repression of WUS transcription through AGAMOUS (AG) activity controls stem cell activity in the determinate floral meristem. Binds to TAAT element core motif. WUS is also involved in cell differentiation during anther development.
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Identifiers

Identifier Name
aliasWUS
aliasWUS1
aliasWUSCHEL
aliasWUSCHEL 1
aliasPGA6
uniprotQ9SB92

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006355TAS, IEAGene Ontologyregulation of transcription, DNA-dependent1
GO:0048653IMPGene Ontologyanther development1
GO:0080166IMPUniProtstomium development1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0010492IGIUniProtmaintenance of shoot apical meristem identity1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0009827RCAGene Ontologyplant-type cell wall modification1
GO:0009860RCAGene Ontologypollen tube growth1
GO:0010093RCAGene Ontologyspecification of floral organ identity1
GO:0048440RCAGene Ontologycarpel development1
GO:0019827IMPGene Ontologystem cell maintenance1
GO:0048477IEAUniProtoogenesis1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0006351IEAUniProttranscription, DNA-templated1 2 3 4 5 6 7 8 9 10 11 12 13
GO:2001141IEAPLAZA Homologyregulation of RNA biosynthetic processHOM03M000493

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003677ISS, IEAGene OntologyDNA binding1
GO:0003700ISS, TASIEA, UniProtsequence-specific DNA binding transcription factor activity1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0005515IPIGene Ontologyprotein binding1
GO:0043565IEAUniProtsequence-specific DNA binding1 2 3 4 5 6 7 8 9 10 11 12 13

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IEA, ISMUniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12 13 14

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001356Homeobox domain
IPR009057Homeodomain-like

Mapman id Description
27.3.22RNA.regulation of transcription.HB,Homeobox transcription factor family
No SignalP domains detected for this gene.
DatabaseType
PlnTFDBHB
PlantTFDBWOX