Gene: AT2G17520 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT2G17520
Transcript Identifier
AT2G17520.1
Gene Type
Coding gene
Location
2 : 7617504-7620929 : positive

Family

Gene family
HOM03M002319
(36 genes in 16 species)
specific family
Subfamily
ORTHO03M023994
(2 genes in 2 species)
specific family

Loading...please wait

Descriptions

Description
Endoribonuclease/protein kinase IRE1-like
Curated Summary
Encodes a endoribonuclease/protein kinase IRE1-like protein that is predicted to form a type I transmembrane protein structure and contain kinase/endoribonuclease domains at their C-terminal halves. The transcript levels for several ER-stress responsive genes, including six protein disulfide isomerases (PDIs), BiP2, and AtbZIP60 are not affected in ire1-2 null mutants.
Show more...

Identifiers

Identifier Name
aliasIRE1A
aliasARABIDOPSIS THALIANA INOSITOL REQUIRING 1-2
aliasIRE1-2
aliasATIRE1-2
aliasINOSITOL REQUIRING 1-2
uniprotQ9C5S2

Toolbox

Explore

View

 

Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006987IMPUniProtactivation of signaling protein activity involved in unfolded protein response1 2 3 4 5 6 7 8 9 10
GO:0046777IMPUniProtprotein autophosphorylation1 2 3 4 5 6 7 8 9 10
GO:0030968IGIGene Ontologyendoplasmic reticulum unfolded protein response1
GO:0008380IMPUniProtRNA splicing1 2 3 4 5 6 7 8 9 10
GO:0009751IMPUniProtresponse to salicylic acid1 2 3 4 5 6 7 8 9 10
GO:0009816IMPUniProtdefense response to bacterium, incompatible interaction1 2 3 4 5 6 7 8 9 10
GO:0006487RCAGene Ontologyprotein N-linked glycosylation1
GO:0006397IEAUniProtmRNA processing1 2 3 4 5 6 7 8 9
GO:0006355IEAUniProtregulation of transcription, DNA-dependent1 2 3 4 5 6 7 8 9
GO:0006351IEAUniProttranscription, DNA-templated1 2 3 4 5 6 7 8 9
GO:0006468IEAInterProprotein phosphorylation

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0016301ISSGene Ontologykinase activity1
GO:0004521IMPUniProtendoribonuclease activity1 2 3 4 5 6 7 8 9 10
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8 9
GO:0046872IEAUniProtmetal ion binding1 2 3 4 5 6 7 8 9
GO:0004674IEAUniProtprotein serine/threonine kinase activity1 2 3 4 5 6 7 8 9
GO:0005515IEAInterProprotein binding
GO:0004672IEAInterProprotein kinase activity
GO:0004540IEAInterProribonuclease activity
GO:0016772IEAInterProtransferase activity, transferring phosphorus-containing groups

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0009507ISMGene Ontologychloroplast1
GO:0005783IDAGene Ontologyendoplasmic reticulum1
GO:0042406IDAUniProtextrinsic to endoplasmic reticulum membrane1 2 3 4 5 6 7 8 9 10
GO:0016021IEAUniProtintegral to membrane1 2 3 4 5 6 7 8 9

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR008271Serine/threonine-protein kinase, active site
IPR010513KEN domain
IPR000719Protein kinase domain
IPR011009Protein kinase-like domain
IPR002290Serine/threonine- / dual specificity protein kinase, catalytic domain
IPR006567PUG domain

Mapman id Description
29.4protein.postranslational modification
SignalP Description
SignalP-noTMSignal Peptide detected using noTM network