Gene: AT2G17290 (Arabidopsis thaliana)

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Gene Identifier
Transcript Identifier
Gene Type
Coding gene
2 : 7517005-7519239 : positive


Gene family
(1515 genes in 16 species)
specific family
Duplication type
Block duplicate

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Calcium-dependent protein kinase family protein
Curated Summary
Encodes calcium dependent protein kinase 6 (CPK6), a member of the Arabidopsis CDPK gene family. CDPKs contain an intrinsic Ca2+-activation domain with four EF hand Ca2+-binding sites. CDPKs protein kinases have been proposed to function in multiple plant signal transduction pathways downstream of [Ca2+]cyt elevations, thus transducing various physiological responses. CPK6 is expressed in both guard cells and mesophyll cells. Functions in guard cell ion channel regulation. ABA and Ca(2+) activation of slow-type anion channels and, interestingly, ABA activation of plasma membrane Ca(2+)-permeable channels were impaired in independent alleles of single and double cpk3cpk6 mutant guard cells. Furthermore, ABA- and Ca(2+)-induced stomatal closing were partially impaired in these cpk3cpk6 mutant alleles. CPK3 is also a member of the Arabidopsis CDPK family.
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Identifier Name
aliascalcium dependent protein kinase 6





Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006468ISS, IEAGene Ontologyprotein phosphorylation1
GO:0009738IMP, RCA, UniProtabscisic acid-activated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0010119IMPUniProtregulation of stomatal movement1 2 3 4 5 6 7 8 9 10 11 12
GO:0010359IMP, RCA, UniProtregulation of anion channel activity1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0009737IDAGene Ontologyresponse to abscisic acid1
GO:0046777IDAUniProtprotein autophosphorylation1 2 3 4 5 6 7 8 9 10 11 12
GO:0000165RCAGene OntologyMAPK cascade1
GO:0006612RCAGene Ontologyprotein targeting to membrane1
GO:0006820RCAGene Ontologyanion transport1
GO:0006862RCAGene Ontologynucleotide transport1
GO:0006888RCAGene OntologyER to Golgi vesicle-mediated transport1
GO:0007154RCAGene Ontologycell communication1
GO:0007165RCAGene Ontologysignal transduction1
GO:0009409RCAGene Ontologyresponse to cold1
GO:0009414RCAGene Ontologyresponse to water deprivation1
GO:0009611RCAGene Ontologyresponse to wounding1
GO:0009723RCAGene Ontologyresponse to ethylene1
GO:0009733RCAGene Ontologyresponse to auxin1
GO:0009753RCAGene Ontologyresponse to jasmonic acid1
GO:0009862RCAGene Ontologysystemic acquired resistance, salicylic acid mediated signaling pathway1
GO:0009867RCAGene Ontologyjasmonic acid mediated signaling pathway1
GO:0010363RCAGene Ontologyregulation of plant-type hypersensitive response1
GO:0015696RCAGene Ontologyammonium transport1
GO:0015802RCAGene Ontologybasic amino acid transport1
GO:0030968RCAGene Ontologyendoplasmic reticulum unfolded protein response1
GO:0031348RCAGene Ontologynegative regulation of defense response1
GO:0035556RCAGene Ontologyintracellular signal transduction1
GO:0042538RCAGene Ontologyhyperosmotic salinity response1
GO:0043069RCAGene Ontologynegative regulation of programmed cell death1
GO:0043090RCAGene Ontologyamino acid import1
GO:0043269RCAGene Ontologyregulation of ion transport1
GO:0050832RCAGene Ontologydefense response to fungus1
GO:0044260IEAPLAZA Homologycellular macromolecule metabolic processHOM03M000021
GO:0006796IEAPLAZA Homologyphosphate-containing compound metabolic processHOM03M000021
GO:0006793IEAPLAZA Homologyphosphorus metabolic processHOM03M000021
GO:0043170IEAPLAZA Homologymacromolecule metabolic processHOM03M000021
GO:0044237IEAPLAZA Homologycellular metabolic processHOM03M000021
GO:0044238IEAPLAZA Homologyprimary metabolic processHOM03M000021
GO:0009987IEAPLAZA Homologycellular processHOM03M000021
GO:0016310IEAPLAZA HomologyphosphorylationHOM03M000021
GO:0008152IEAPLAZA Homologymetabolic processHOM03M000021
GO:0043412IEAPLAZA Homologymacromolecule modificationHOM03M000021
GO:0071704IEAPLAZA Homologyorganic substance metabolic processHOM03M000021
GO:0044267IEAPLAZA Homologycellular protein metabolic processHOM03M000021
GO:0006464IEAPLAZA Homologycellular protein modification processHOM03M000021
GO:0036211IEAPLAZA Homologyprotein modification processHOM03M000021
GO:0019538IEAPLAZA Homologyprotein metabolic processHOM03M000021

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004683ISSGene Ontologycalmodulin-dependent protein kinase activity1
GO:0016301ISSGene Ontologykinase activity1
GO:0005515IPIGene Ontologyprotein binding1
GO:0004674IDA, IEA, UniProtprotein serine/threonine kinase activity1 2 3 4 5 6 7 8 9 10 11 12
GO:0005524IEAUniProtATP binding1 2 3 4 5 6 7 8 9 10 11
GO:0005509IEAUniProtcalcium ion binding1 2 3 4 5 6 7 8 9 10 11
GO:0004672IEAInterProprotein kinase activity
GO:0016772IEAInterProtransferase activity, transferring phosphorus-containing groups
GO:0032555IEAPLAZA Homologypurine ribonucleotide bindingHOM03M000021
GO:0043168IEAPLAZA Homologyanion bindingHOM03M000021
GO:0032553IEAPLAZA Homologyribonucleotide bindingHOM03M000021
GO:0043167IEAPLAZA Homologyion bindingHOM03M000021
GO:0035639IEAPLAZA Homologypurine ribonucleoside triphosphate bindingHOM03M000021
GO:0097367IEAPLAZA Homologycarbohydrate derivative bindingHOM03M000021
GO:0003824IEAPLAZA Homologycatalytic activityHOM03M000021
GO:0032559IEAPLAZA Homologyadenyl ribonucleotide bindingHOM03M000021
GO:1901265IEAPLAZA Homologynucleoside phosphate bindingHOM03M000021
GO:0000166IEAPLAZA Homologynucleotide bindingHOM03M000021
GO:0001882IEAPLAZA Homologynucleoside bindingHOM03M000021
GO:0030554IEAPLAZA Homologyadenyl nucleotide bindingHOM03M000021
GO:0016773IEAPLAZA Homologyphosphotransferase activity, alcohol group as acceptorHOM03M000021
GO:0097159IEAPLAZA Homologyorganic cyclic compound bindingHOM03M000021
GO:0017076IEAPLAZA Homologypurine nucleotide bindingHOM03M000021
GO:0036094IEAPLAZA Homologysmall molecule bindingHOM03M000021
GO:0032549IEAPLAZA Homologyribonucleoside bindingHOM03M000021
GO:1901363IEAPLAZA Homologyheterocyclic compound bindingHOM03M000021
GO:0005488IEAPLAZA HomologybindingHOM03M000021
GO:0001883IEAPLAZA Homologypurine nucleoside bindingHOM03M000021
GO:0016740IEAPLAZA Homologytransferase activityHOM03M000021
GO:0032550IEAPLAZA Homologypurine ribonucleoside bindingHOM03M000021

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1
GO:0016020TASGene Ontologymembrane1
GO:0005886IDAUniProtplasma membrane1 2 3 4 5 6 7 8 9 10 11 12
GO:0005829IDA, RCA, UniProtcytosol1 2 3 4 5 6 7 8 9 10 11 12 13

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR018247EF-Hand 1, calcium-binding site
IPR002048EF-hand domain
IPR011992EF-hand domain pair
IPR008271Serine/threonine-protein kinase, active site
IPR000719Protein kinase domain
IPR002290Serine/threonine- / dual specificity protein kinase, catalytic domain
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

Mapman id Description
No SignalP domains detected for this gene.