Gene: AT2G01980 (Arabidopsis thaliana)

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Gene Identifier
AT2G01980
Transcript Identifier
AT2G01980.1
Gene Type
Coding gene
Location
2 : 457070-463145 : positive

Family

Gene family
HOM03M003293
(27 genes in 16 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
sodium proton exchanger, putative (NHX7) (SOS1)
Curated Summary
Encodes a plasma membrane-localized Na+/H+ antiporter SOS1. Functions in the extrusion of toxic Na+ from cells and is essential for plant salt tolerance. Has 12 predicted transmembrane domains in the N-terminal region and a long cytoplasmic tail of approx. 700 aa at the C-terminal side. SOS1 interacts through its predicted cytoplasmic tail with RCD1, a regulator of oxidative-stress responses, suggesting that SOS1 might function in oxidative-stress tolerance.
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Identifiers

Identifier Name
aliasATNHX7
aliasARABIDOPSIS NA+/H+ ANTIPORTER 7
aliasSOS1
aliasARABIDOPSIS SALT OVERLY SENSITIVE 1
aliasSALT OVERLY SENSITIVE 1
aliasATSOS1
uniprotQ9LKW9

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006814IMP, ISSRCA, UniProtsodium ion transport1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
GO:0035725ISSGene Ontologysodium ion transmembrane transport1
GO:0009651IMP, IEPUniProtresponse to salt stress1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0010163IMPUniProthigh-affinity potassium ion import1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0042542IMP, IEPUniProtresponse to hydrogen peroxide1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:2000377IMPUniProtregulation of reactive oxygen species metabolic process1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0000302IEPGene Ontologyresponse to reactive oxygen species1
GO:0006979IMPGene Ontologyresponse to oxidative stress1
GO:0006816RCAGene Ontologycalcium ion transport1
GO:0006869RCAGene Ontologylipid transport1
GO:0006891RCAGene Ontologyintra-Golgi vesicle-mediated transport1
GO:0010351RCAGene Ontologylithium ion transport1
GO:0016558RCAGene Ontologyprotein import into peroxisome matrix1
GO:0055085IEAInterProtransmembrane transport
GO:0006812IEAInterProcation transport
GO:0055078ISOPLAZA Integrative Orthologysodium ion homeostasisSL01G005020

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0015385ISSGene Ontologysodium:hydrogen antiporter activity1
GO:0005515IPIGene Ontologyprotein binding1
GO:0015299IEAUniProtsolute:hydrogen antiporter activity1 2 3 4 5 6 7 8 9 10 11 12 13

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005886IDA, ISM, UniProtplasma membrane1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
GO:0009941IDAUniProtchloroplast envelope1 2 3 4 5 6 7 8 9 10 11 12 13 14
GO:0016021IEAUniProtintegral to membrane1 2 3 4 5 6 7 8 9 10 11 12 13

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR018490Cyclic nucleotide-binding-like
IPR006153Cation/H+ exchanger
IPR018418Na+/H+ exchanger, isoforms 7/8
IPR018422Cation/H+ exchanger, CPA1 family
IPR000595Cyclic nucleotide-binding domain

Mapman id Description
34.14transport.unspecified cations
No SignalP domains detected for this gene.