Gene: AT1G80360 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G80360
Transcript Identifier
AT1G80360.1
Gene Type
Coding gene
Location
1 : 30208736-30210643 : negative

Family

Gene family
HOM03M004423
(21 genes in 14 species)
specific family
Subfamily
ORTHO03M006282
(6 genes in 6 species)
specific family

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Descriptions

Description
Pyridoxal phosphate (PLP)-dependent transferases superfamily protein
Curated Summary
Encodes a methionine-specific aminotransferase that uses the ethylene biosynthetic intermediate methionine as an amino donor and the auxin biosynthetic intermediate indole-3-pyruvic acid as an amino acceptor to produce L-tryptophan and 2-oxo-4-methylthiobutyric acid. These actions allow VAS1 to coordinate both auxin and ethylene biosynthesis. It functions downstream of TAA1/SAV3 but upstream of YUCs to negatively modulate IAA biosynthesis directly by altering the 3-IPA pool.
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Identifiers

Identifier Name
aliasreversal of sav3 phenotype 1
aliasVAS1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009641IMPGene Ontologyshade avoidance1
GO:0009851IMPGene Ontologyauxin biosynthetic process1
GO:0010366IMPGene Ontologynegative regulation of ethylene biosynthetic process1
GO:1901997IDAGene Ontologynegative regulation of indoleacetic acid biosynthetic process via tryptophan1
GO:0009058IEAInterProbiosynthetic process

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0008483ISSGene Ontologytransaminase activity1
GO:0010326IDAGene Ontologymethionine-oxo-acid transaminase activity1
GO:0030170IEAInterPropyridoxal phosphate binding
GO:0003824IEAInterProcatalytic activity

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737IDA, ISMGene Ontologycytoplasm1 2
GO:0005829IDAGene Ontologycytosol1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR015422Pyridoxal phosphate-dependent transferase, major region, subdomain 2
IPR004838Aminotransferases, class-I, pyridoxal-phosphate-binding site
IPR015421Pyridoxal phosphate-dependent transferase, major region, subdomain 1
IPR015424Pyridoxal phosphate-dependent transferase
IPR004839Aminotransferase, class I/classII

Mapman id Description
13.1.6.2amino acid metabolism.synthesis.aromatic aa.phenylalanine and tyrosine
No SignalP domains detected for this gene.