Gene: AT1G77300 (Arabidopsis thaliana)

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Gene Identifier
AT1G77300
Transcript Identifier
AT1G77300.1
Gene Type
Coding gene
Location
1 : 29040160-29048810 : negative

Family

Gene family
HOM03M001151
(63 genes in 14 species)
specific family

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Descriptions

Description
histone methyltransferases(H3-K4 specific);histone methyltransferases(H3-K36 specific)
Curated Summary
Encodes a protein with histone lysine N-methyltransferase activity required specifically for the trimethylation of H3-K4 in FLC chromatin (and not in H3-K36 dimethylation). Acts as an inhibitor of flowering specifically involved in the autonomous promotion pathway. EFS also regulates the expression of genes involved in carotenoid biosynthesis.Modification of histone methylation at the CRTISO locus reduces transcript levels 90%. The increased shoot branching seen in some EFS mutants is likely due to the carotenoid biosynthesis defect having an effect on stringolactones.Required for ovule, embryo sac, anther and pollen development.
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Identifiers

Identifier Name
aliasSDG8
aliasSET DOMAIN GROUP 8
aliasEARLY FLOWERING IN SHORT DAYS
aliasEFS
aliasLAZ2
aliasASH1 HOMOLOG 2
aliasASHH2
aliasCAROTENOID CHLOROPLAST REGULATORY1
aliasLAZARUS 2
aliasCCR1
uniprotQ2LAE1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0009910IMPUniProtnegative regulation of flower development1 2 3 4 5 6 7 8 9 10 11 12
GO:0031062IDAUniProtpositive regulation of histone methylation1 2 3 4 5 6 7 8 9 10 11 12
GO:0010223IMPUniProtsecondary shoot formation1 2 3 4 5 6 7 8 9 10 11 12
GO:0016116IMPUniProtcarotenoid metabolic process1 2 3 4 5 6 7 8 9 10 11 12
GO:0040029IMPUniProtregulation of gene expression, epigenetic1 2 3 4 5 6 7 8 9 10 11 12
GO:0009553IMPUniProtembryo sac development1 2 3 4 5 6 7 8 9 10 11 12
GO:0009555IMPUniProtpollen development1 2 3 4 5 6 7 8 9 10 11 12
GO:0010452IDAUniProthistone H3-K36 methylation1 2 3 4 5 6 7 8 9 10 11 12
GO:0048481IMPUniProtovule development1 2 3 4 5 6 7 8 9 10 11 12
GO:0048653IMPUniProtanther development1 2 3 4 5 6 7 8 9 10 11 12
GO:0010363IMPUniProtregulation of plant-type hypersensitive response1 2 3 4 5 6 7 8 9 10 11 12
GO:0043067IGIGene Ontologyregulation of programmed cell death1
GO:0034968IEAUniProthistone lysine methylation1 2 3 4 5 6 7 8 9 10 11

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0042800IDAUniProthistone methyltransferase activity (H3-K4 specific)1 2 3 4 5 6 7 8 9 10 11 12
GO:0046975IDAGene Ontologyhistone methyltransferase activity (H3-K36 specific)1
GO:0018024IEAUniProthistone-lysine N-methyltransferase activity1 2 3 4 5 6 7 8 9 10 11
GO:0008270IEAUniProtzinc ion binding1 2 3 4 5 6 7 8 9 10 11
GO:0005515IEAInterProprotein binding

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISMIEA, UniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12 13
GO:0000775IEAUniProtchromosome, centromeric region1 2 3 4 5 6 7 8 9 10 11

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006560AWS
IPR001214SET domain
IPR011124Zinc finger, CW-type
IPR003616Post-SET domain

Mapman id Description
27.3.69RNA.regulation of transcription.SET-domain transcriptional regulator family
No SignalP domains detected for this gene.
DatabaseType
PlnTFDBSET