Gene: AT1G77000 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT1G77000
Transcript Identifier
AT1G77000.1
Gene Type
Coding gene
Location
1 : 28940888-28942401 : positive

Family

Gene family
HOM03M002886
(30 genes in 15 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
RNI-like superfamily protein
Curated Summary
AtSKP2;2 is a homolog of human SKP2, the human F-box protein that recruits E2F1. Contains an F-box motif at the N-terminal region and a C-terminal Leu-rich repeat domain. Forms part of an E3-ubiquitin-ligase SCF (Skp1, cullin, F-box) complex and recruits phosphorylated AtE2Fc, a transcriptional factor that might play a role in cell division and during the transition from skotomorphogenesis to photomorphogenesis. AtSKP2;1 (At1g21410) and AtSKP2;2 (At1g77000) may be duplicated genes. AtSKP2b may also be involved in the degradation of KRP1/ICK1, a CDK inhibitor.
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Identifiers

Identifier Name
aliasATSKP2;2
aliasARABIDOPSIS HOMOLOG OF HOMOLOG OF HUMAN SKP2 2
aliasSKP2B
uniprotO49286

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006511TASGene Ontologyubiquitin-dependent protein catabolic process1
GO:0010286IEP, RCA, UniProtheat acclimation1 2 3 4 5 6 7
GO:0051603IMPUniProtproteolysis involved in cellular protein catabolic process1 2 3 4 5 6
GO:1901332IMPUniProtnegative regulation of lateral root development1 2 3 4 5 6
GO:0031146ISOPLAZA Integrative OrthologySCF-dependent proteasomal ubiquitin-dependent protein catabolic processAT1G21410
GO:0010311ISOPLAZA Integrative Orthologylateral root formationAT1G21410
GO:0051781ISOPLAZA Integrative Orthologypositive regulation of cell divisionAT1G21410
GO:0016567ISOPLAZA Integrative Orthologyprotein ubiquitinationAT1G21410
GO:0071365ISOPLAZA Integrative Orthologycellular response to auxin stimulusAT1G21410

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004842ISSGene Ontologyubiquitin-protein ligase activity1
GO:0005515IEAInterProprotein binding

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634ISMGene Ontologynucleus1
GO:0019005ISOPLAZA Integrative OrthologySCF ubiquitin ligase complexAT1G21410

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001810F-box domain
IPR006553Leucine-rich repeat, cysteine-containing subtype

Mapman id Description
29.5.11.4.3.2protein.degradation.ubiquitin.E3.SCF.FBOX
No SignalP domains detected for this gene.