Gene: AT1G75950 (Arabidopsis thaliana)

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Gene Identifier
AT1G75950
Transcript Identifier
AT1G75950.1
Gene Type
Coding gene
Location
1 : 28516715-28517454 : positive

Family

Gene family
HOM03M000303
(182 genes in 16 species)
specific family
Duplication type
Block duplicate

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Descriptions

Description
S phase kinase-associated protein 1
Curated Summary
SKP1 is core component of the SCF family of E3 ubiquitin ligases and serves to tether the rest of the complex to an F-box protein, which provides specificity in binding to ubiquitin ligase substrate proteins. Predominately expressed from leptotene to pachytene. Negatively regulates recombination. Interacts with P0, a silencing suppressor protein encoded by poleroviruses by means of a conserved minimal F-box motif.
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Identifiers

Identifier Name
aliasUIP1
aliasUFO INTERACTING PROTEIN 1
aliasS phase kinase-associated protein 1
aliasASK1
aliasARABIDOPSIS SKP1 HOMOLOGUE 1
aliasSKP1
aliasSKP1A
aliasATSKP1
uniprotQ39255

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007140IMPGene Ontologymale meiosis1
GO:0006511IEA, RCA, TASUniProtubiquitin-dependent protein catabolic process1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38
GO:0045910IMPUniProtnegative regulation of DNA recombination1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
GO:0046686IEPUniProtresponse to cadmium ion1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
GO:0000226IMPUniProtmicrotubule cytoskeleton organization1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
GO:0007067RCA, TASGene Ontologymitosis1 2
GO:0042023RCAGene OntologyDNA endoreduplication1
GO:0042752RCAGene Ontologyregulation of circadian rhythm1
GO:0043161RCAGene Ontologyproteasome-mediated ubiquitin-dependent protein catabolic process1
GO:0043248RCAGene Ontologyproteasome assembly1
GO:0051510RCAGene Ontologyregulation of unidimensional cell growth1
GO:0051788RCAGene Ontologyresponse to misfolded protein1
GO:0009734IEAUniProtauxin mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
GO:0007059IEAUniProtchromosome segregation1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
GO:0009873IEAUniProtethylene mediated signaling pathway1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
GO:0019048IEAUniProtmodulation by virus of host morphology or physiology1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
GO:0007275IEAUniProtmulticellular organismal development1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
GO:0016567IEAUniProtprotein ubiquitination1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36
GO:0044265IEAPLAZA Homologycellular macromolecule catabolic processHOM03M000303
GO:0009057IEAPLAZA Homologymacromolecule catabolic processHOM03M000303
GO:0043632IEAPLAZA Homologymodification-dependent macromolecule catabolic processHOM03M000303
GO:0030163IEAPLAZA Homologyprotein catabolic processHOM03M000303
GO:0051603IEAPLAZA Homologyproteolysis involved in cellular protein catabolic processHOM03M000303
GO:0019941IEAPLAZA Homologymodification-dependent protein catabolic processHOM03M000303
GO:0044248IEAPLAZA Homologycellular catabolic processHOM03M000303
GO:0044257IEAPLAZA Homologycellular protein catabolic processHOM03M000303

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004842ISSGene Ontologyubiquitin-protein ligase activity1
GO:0005515IPIGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634IDA, ISMNAS, UniProtnucleus1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39
GO:0005737NASGene Ontologycytoplasm1
GO:0019005NASGene OntologySCF ubiquitin ligase complex1
GO:0000151TASGene Ontologyubiquitin ligase complex1
GO:0005819IDAUniProtspindle1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
GO:0009524IDAUniProtphragmoplast1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
GO:0005886IDAUniProtplasma membrane1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
GO:0005829IDAUniProtcytosol1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011333BTB/POZ fold
IPR016072SKP1 component, dimerisation
IPR001232SKP1 component
IPR016073SKP1 component, POZ domain

Mapman id Description
29.5.11.4.3.1protein.degradation.ubiquitin.E3.SCF.SKP
No SignalP domains detected for this gene.